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Chinese medicinal composition for treating painful swelling of throat and constipation, and preparation method thereof

A technology for constipation and sore throat, which can be used in drug combinations, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., and can solve problems such as low bioavailability, large swallowing volume, and incomplete absorption.

Inactive Publication Date: 2009-06-24
津药达仁堂集团股份有限公司达仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Qingjiang Pills and Qingjiang Tablets are pure traditional Chinese medicine preparations with remarkable curative effect. Their main functions are to clear away heat and detoxify, sore throat and relieve pain. The utilization rate is not high, especially not suitable for swallowing by children, so it is of great significance to develop a high-efficiency, low-toxicity, heat-clearing and detoxifying, relieving sore throat and pain-relieving preparation that is suitable for children to swallow

Method used

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  • Chinese medicinal composition for treating painful swelling of throat and constipation, and preparation method thereof
  • Chinese medicinal composition for treating painful swelling of throat and constipation, and preparation method thereof
  • Chinese medicinal composition for treating painful swelling of throat and constipation, and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0066] Embodiment 1: Chinese medicine composition for treating sore throat and constipation. Preparation of Qingjiang Gel:

[0067] 1) Preparation prescription:

[0068]

[0069] 2) Preparation method: according to claim 1, the raw material drug composition of the active ingredient is fed:

[0070] Rhubarb powder is made into the coarsest powder, mixed with Indigo Daisy, Scrophulariaceae, and Fritillaria, and extracted twice with 80% ethanol, each time for 1.5 hours, combined with the alcohol extract, recovered ethanol and concentrated into a paste, with a relative density of 1.30-1.35 , 60°C;

[0071] Moutan cortex is made into the coarsest powder, mixed with silkworm excrement, saponin, red peony root, Ophiopogon japonicus, forsythia, honeysuckle, banlangen, rehmannia root, Imperata rhizome, mint, licorice, and boiled twice with 10 times the amount of water, each time After 1.5 hours, collect the volatile oil, filter the water extract several times, combine the filtrate...

Embodiment 2

[0073] Embodiment 2: Qingjiang gel quality standard

[0074] [Prescription] Silkworm excrement 400 Rhubarb 400 Scrophulariaceae 400 Saponaria 400 Radix Paeoniae Rubra 400 Ophiopogon japonicus 400 Forsythia 400 Banlangen 400 Rehmannia glutinosa 400 Honeysuckle 400 Imperata rhizome 400 Peony bark 260 Indigo Daisy 200 Fritillaria 200 Mint 200 Licorice 132

[0075] [Preparation method] The above sixteen flavors, rhubarb powder into the coarsest powder, mixed with Qingdai, Scrophulariaceae, Chuan Fritillaria, add 8 times the amount of 80% ethanol to extract twice, each time for 1.5 hours, combine alcohol extracts, recover ethanol and concentrate Make a paste (relative density 1.30-1.35, 60°C). Moutan cortex is ground into the coarsest powder, mixed with silkworm excrement, saponins, red peony root, Ophiopogon japonicus, forsythia, honeysuckle, banlangen, rehmannia root, courgette root, mint, licorice, add 10 times the amount of water to decoct twice, each time After 1.5 hours, col...

Embodiment 3

[0096] Example 3: Drafting instructions for the quality standard draft of Qingjiang gel

[0097] This product is a gel made from silkworm excrement, rhubarb and other sixteen medicinal materials, which are extracted, mixed and made respectively. The relevant issues in the quality standard draft of Qingjiang Gel are explained as follows:

[0098] The gel under the item [properties] of this standard is in the form of gel, and after being separated from the packaging container, it can basically maintain the original shape, the tissue is soft and moderate, full of elasticity, fine and uniform, and there is no obvious floc.

[0099] Under this standard [identification]

[0100] (1) For the TLC identification test of Radix Paeoniae Rubra in the prescription, paeoniflorin was used as the reference substance, and a negative sample lacking Radix Paeoniae Rubra was made according to the prescription ratio, and the negative control solution was prepared according to the preparation meth...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation, and relates to a traditional Chinese medicine composition for treating sore throat and constipation and a preparation method thereof, in particular to a medicament prepared from the raw material medicine with effective components such as silkworm excrement, rhubarb, figwort, Chinese honeylocust fruit, red paeony root, dwarf lilyturf turber, forsythia, radix isatidis, rehmannia, honeysuckle, rhizome imperatae, tree peony bark, natural indigo, fritillaria cirrhosa, mint, and licorice and used for clearing away heat and toxic materials, relieving sore throat and pain, and treating diseases such as sore throat caused by pneumogastric intrinsic heat, fever and fidget, constipation, children acute pharyngitis, acute tonsillitis, and the like and a preparation method thereof. The invention also discloses a recipe for gelata prepared by extracting and mixing sixteen medicinal materials such as silkworm excrement, rhubarb and the like, quality standard, and a quality inspection method. The dosage form has the advantages of convenience for taking and carrying, good mouth feel, and easy acceptance by children, overcomes the defect that pills and tablets are difficult for the children to take, and is remarkably superior to cleaning pills.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a kind of heat-clearing and detoxifying, relieving sore throat and relieving pain, which is used for sore throat, fever, irritability, constipation, acute pharyngitis in children, and acute tonsillitis caused by accumulation of heat in the lung and stomach. The medicine and preparation method thereof, the present invention also relates to the prescription, quality standard and quality inspection method of the Qingjiang gel. Background technique [0002] Acute pharyngitis (acute pharyngitis) is the acute inflammation of the pharyngeal mucosa and spreads to the submucosal and lymphoid tissues, often secondary to acute rhinitis or acute tonsils or part of upper respiratory tract infection. It is also often a local manifestation of a systemic disease or a prodrome of an acute infectious disease. Often due to cold, excessive fatigue, exce...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K47/36A61P1/10A61P11/04G01N30/90
Inventor 金兆祥张忠诚罗辉刘彤张彤云
Owner 津药达仁堂集团股份有限公司达仁堂制药厂
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