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Eyedrops for treating xerophthalmia

A technology for eye drops and dry eye disease, applied in sensory diseases, medical formulas, drug combinations, etc., can solve the problems of no antibacterial and antibacterial effects, inconvenient practical use, and short residence time of active ingredients of drugs, so as to relieve eye discomfort , Long stay time, remarkable curative effect

Inactive Publication Date: 2009-07-01
SHANGHAI HUIKANG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After the medicine of this type of preparation is instilled into the eyes, the residence time of the active ingredient of the medicine is short, and the bioavailability of the medicine is low
The second is to make the active ingredient of the drug into a paste. Although this preparation prolongs the residence time of the active ingredient of the drug in the eyes, it is very inconvenient to use
However, enhancers such as hyaluronic acid have no antibacterial and antibacterial effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Dissolve 5g carboxybutyl chitosan, 2.5g ofloxacin, and 35g sodium chloride in an appropriate amount of distilled water, then adjust the pH value to 7.0 with an appropriate amount of 200ul sodium hydroxide, mix well, add distilled water to 1000ml, and use 0.2um The microporous membrane is filtered and sterilized, and sealed after subpackaging to obtain the eye drops of the present invention.

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PUM

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Abstract

The invention belongs to the technical field of medicament, specifically relates to an eye drop having functions of easing indisposition and weariness of eyes, particularly treating xerophthalmus. The main active ingredient of the formula of the eye drop is carboxymethyl chitosan. The invention has long lasting effect and antibacterial function, thereby bioavailability of medicament is improved.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular, the invention belongs to an eye drop for treating dry eye disease. Background technique [0002] With the acceleration of the pace of life, the abnormal climate and the increase in computer usage, the incidence of eye diseases such as eye discomfort, eye fatigue, and dry eye disease is getting higher and higher. At present, there are mainly three types of eye drops for the clinical treatment of eye diseases. One is to dissolve antibiotics or antiviral drugs directly in distilled water and use them at a certain concentration. After the medicine of this type of preparation is instilled into the eyes, the residence time of the active ingredient of the medicine is short, and the bioavailability of the medicine is low. The second is to make the active ingredient of the medicine into a paste. Although this preparation prolongs the residence time of the active ingredient of the medicin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K47/36A61K31/722A61K31/5383A61P27/02
Inventor 李峰
Owner SHANGHAI HUIKANG BIOTECH
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