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Medicament composition with stone-eliminating and expelling functions and preparation method thereof

A composition and stone-removing technology, which are applied in the directions of drug combinations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve problems such as reducing the dosage used, and achieve a small dosage and high content of active ingredients. , Overcome the effect of easy moisture absorption

Inactive Publication Date: 2009-07-22
SICHUAN XUHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is difficult for those skilled in the art to predict whether the drug can be maintained or improved after the drug is prepared into a pill, and the dosage can be reduced.

Method used

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  • Medicament composition with stone-eliminating and expelling functions and preparation method thereof
  • Medicament composition with stone-eliminating and expelling functions and preparation method thereof
  • Medicament composition with stone-eliminating and expelling functions and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1 The preparation of medicine pill of the present invention

[0026] Raw materials of Chinese herbal medicine (unit: gram):

[0027] Money Grass 750g Wangbuliuxing (Stir-fried) 750g 450g

[0028] Yanhusuo (made with vinegar) 225g Chicken Inner Gold (hot) 300g Salvia miltiorrhiza 300g

[0029] Woody fragrance 150g Qumai 375g Achyranthes bidentata 225g

[0030] Sea Sands 300g

[0031] medical supplements:

[0032] Starch 550g

[0033] Its preparation method is, among the above-mentioned 10 flavors of Chinese herbal medicines, take Haijinsha and Wangbuliuxing and put them into a cloth bag, add water to decoct with the other eight flavors such as Desmodium syringae for two times, add 10 times the amount of water each time, and add water for the first time Extract for 2.5 hours, extract for the second time for 1.0 hours, combine the decoction, filter, and concentrate under reduced pressure (75°C, -0.07Mpa) to an extract with a relative density of 1.20 (80°C);...

Embodiment 2

[0034] Embodiment 2 The preparation of medicine pill of the present invention

[0035] Raw materials of Chinese herbal medicine:

[0036] Money Grass 17.1% Chao Wang Bu Liu Xing 17.1% Savings 10.3%

[0037] Vinegar Corydalis 5.1% Hot Chicken Neijin 6.9% Salvia 6.9%

[0038] Woody 3.4% Quma 8.6% Achyranthes 5.1%

[0039] Sea Sands 6.9%

[0040] medical supplements:

[0041] Starch 12.6%

[0042] Its preparation method is, among the above-mentioned 10 flavors of Chinese herbal medicines, take Haijinsha and Wangbuliuxing and put them into a cloth bag, add water to decoct with the other eight flavors such as Desmodium syringae for two times, add 10 times the amount of water each time, and add water for the first time Extract for 2.5 hours, extract for the second time for 1.0 hours, combine the decoction, filter, and concentrate under reduced pressure (75°C, -0.07Mpa) to an extract with a relative density of 1.20 (80°C); add starch and mix with the extract, mix Paste, dried u...

Embodiment 3

[0043] Embodiment 3 The preparation of medicine pill of the present invention

[0044] Raw materials of Chinese herbal medicine:

[0045] Money Grass 15% Fried King Bu Liu Xing 15% Pian Saving 12%

[0046] Vinegar Corydalis 6% Hot Chicken Neijin 8% Salvia 8%

[0047] Woody 3% Quma 8% Achyranthes 6%

[0048] Sea Sands 8%

[0049] medical supplements:

[0050] Starch 11%

[0051] Its preparation method is, among the above-mentioned 10 flavors of Chinese herbal medicines, take Haijinsha and Wangbuliuxing and put them into a cloth bag, add water to decoct with the other eight flavors such as Desmodium syringae for two times, add 10 times the amount of water each time, and add water for the first time Extract for 2.5 hours, extract for the second time for 1.0 hours, combine the decoction, filter, and concentrate under reduced pressure (75°C, -0.07Mpa) to an extract with a relative density of 1.25 (75°C); add starch and mix with the extract, mix Paste, dried under reduced pres...

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Abstract

The invention provides a medical composition with functions of dissolving and discharging stones, which is pills prepared from Herba Lysimachiae, stir-fried cowherb seed, Common Knotgrass Herb, Corydalis tuber processed by vinegar, scalded Endothelium Corneum Gigeriae Galli, Salvia Miltrorrhiza, Radix Aucklandiae, fringed pink, Radix Cyathulae, Japanese Climbing Fern Spore and a pharmaceutic adjuvant starch. The preparation method for the medical composition comprises that: firstly mixing an extract with the starch of which the weight is twice of that of the extract for stirring; drying the mixture at a temperature of 70 DEG C and reduced pressure of -0.07MPa; crushing the mixture into fine powder; mixing the fine powder evenly and preparing the fine powder into pillet mother nucleuses by water; and adding the residual starch gradually to coat the mother nucleuses to prepare pellets, and drying the pellets. The outsides of the mother nucleuses are coated with the starch, so that the pellets cannot stick and keep round and smooth when dried, the difficult problem that pellets cannot be prepared is solved, and the defect that granules are easy to absorb damp is overcome. The preparation has the advantages of safe administration, accurate dosage, controllable quality, reliable healing effect, high contents of effective ingredients, small administrative dosage, convenient administration, and sugar-free to be suitable for more patients.

Description

technical field [0001] The invention relates to a pharmaceutical composition with fossil and calculus-dispelling functions; the invention also relates to a preparation method of the medicine, which belongs to the field of traditional Chinese medicines. Background technique [0002] Shenshitong Granule is a classic Chinese patent medicine. It is made into granules of ten Chinese herbal medicines including money grass, stir-fried wang buliu xing, pianzhu, vinegar-made yanhusuo, hot chicken inner gold, salvia miltiorrhiza, woody incense, oatmeal, achyranthes bidentata, and sea jinsha. The Shenshitong granule has the functions of clearing away heat and promoting dampness, promoting blood circulation and relieving pain, removing fossils and removing stones, and is used for clinical treatment of diseases such as kidney stones, renal pelvis stones, ureteral stones and the like. However, the preparation is a granule, and the dosage form is relatively backward. The dosage of the gra...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K9/20A61P13/04A61K35/37A61K47/36A61K35/57
Inventor 谢李李伟张文杰
Owner SICHUAN XUHUA PHARMA
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