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Use of kuhseng total-flavone in preparing medicine

A total flavonoids of Sophora flavescens and a technology for preparing medicines are applied in the directions of medicine combinations, medicine formulations, plant raw materials, etc., to achieve the effects of no toxic and side effects, reliable curative effect and abundant resources.

Active Publication Date: 2009-08-19
DALIAN MEDICAL UNIVERSITY
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Problems solved by technology

[0009] The invention patent application with the Chinese patent application number 200410030937.X discloses "a total flavonoid extract from Sophora flavescens and its preparation method and application". diseases, but there is no report on its anti-osteoporosis effect

Method used

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  • Use of kuhseng total-flavone in preparing medicine
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  • Use of kuhseng total-flavone in preparing medicine

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Embodiment Construction

[0021] The method described in the prior art can be used to extract the total flavonoids of Sophora flavescens, and the following method can also be used to extract:

[0022] Take 1Kg of Sophora flavescens medicinal material, crush it, pass through an 80-mesh sieve, add 20 times of 10% hydrochloric acid solution, soak for 5 hours, filter, and wash with 3 times of water. The medicinal material residues were dried, extracted twice with 20 times of ethanol, the extracts were combined, and concentrated to dryness under reduced pressure to obtain a crude extract. Use 3 times the amount of ethyl acetate to dissolve the crude extract, wash it once with equal volumes of 5% hydrochloric acid solution, 5% sodium carbonate solution and water, and then recover the ethyl acetate solution under reduced pressure to obtain bitter The total flavonoid extract of ginseng (40 grams), based on the compound kurarinone, has a total flavonoid content of 51.5%.

[0023] The total flavonoid extract of...

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Abstract

The invention discloses application of general flavone in sophora flavescens in preparing a medicine. The invention is characterized by application of flavonone and flavonone alcohols derivatives in preparing an anti-osteoporosis medicine. The application has the advantages of reliable healing efficacy, non toxic or side effects, rich resource, low price and the like.

Description

Technical field: [0001] The invention relates to a new application of total flavonoids of Sophora flavescens in preparing medicines, in particular to an application of total flavonoids of Sophora flavescens in preparing medicines for treating osteoporosis. Background technique: [0002] According to the statistics of the World Health Organization (WHO), osteoporosis (osteoporosis) ranks the 5th among common frequently-occurring diseases, and the total number of patients in the world exceeds 300 million people, and there are a large number of potential patients. At present, the treatment drugs for osteoporosis mainly include three categories: the first category is bone-promoting drugs, such as anabolic hormones; the second category is anti-bone absorption drugs, such as estrogen; the third category is vitamin D, which promotes Bone mineralization drugs, and these drugs all have the disadvantages of high cost and large side effects. [0003] Sophora flavescens (Sophora flaves...

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Application Information

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IPC IPC(8): A61K36/489A61P19/10A61K125/00A61K31/352
Inventor 马骁驰孙长凯张宝璟刘克辛
Owner DALIAN MEDICAL UNIVERSITY
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