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Polymeric coatings and methods for forming them

一种聚合物、表面涂层的技术，应用在涂层等方向，能够解决限制适用性等问题

Inactive Publication Date: 2009-09-09
COMMONWEALTH SCI & IND RES ORG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as discussed previously, surface modification protocols designed for specific substrates such as silica and polystyrene severely limit the applicability of this technique

Method used

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  • Polymeric coatings and methods for forming them
  • Polymeric coatings and methods for forming them
  • Polymeric coatings and methods for forming them

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 15

[0162] Example 15 demonstrates another coating containing copolymerizable biotin, which involves the synthesis of polymerizable biotin derivatives used to prepare the coating.

Embodiment 16

[0163] Example 16 illustrates a method of making a coating according to one embodiment of the invention using an ATRP initiator introduced into the polymer by copolymerization.

Embodiment 17

[0164] Example 17 demonstrates the synthesis of another coating containing copolymerizable N-acryloyloxysuccinimide, and the use of such coatings in conjunction with pentapeptides to modulate the cell-binding properties of coated substrates.

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Abstract

The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerisation initiators.

Description

technical field [0001] The present invention relates to methods and processes for modifying the surface of various substrate materials, including organic and inorganic substrates. More specifically, the present invention relates to at least partially coating a substrate surface with a polymer to impart functional properties to the substrate surface that are distinct from the functional properties of the remainder of the substrate. For example, in biomedical applications, a functional property imparted to the surface of a substrate may be the ability to induce a specific biological response. Background technique [0002] In many applications it is important to differentiate between the bulk properties of a material or device and the surface properties of the material or device. The host or substrate material provides a set of host properties suitable for the intended application, such as mechanical or refractive properties. In many applications, however, the surface propert...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C09D201/02C08L101/02
CPCC08J7/123
Inventor 劳伦斯·马尔赫尔穆特·西森保罗·帕西克理查德·A·伊万斯格雷厄姆·约翰森
Owner COMMONWEALTH SCI & IND RES ORG
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