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Method for making three-dimensional visualization model of internal structure of bone

A technology of internal structure and production method, which is applied in the field of digital three-dimensional visualization model production of bone internal structure, and can solve problems such as limited application

Inactive Publication Date: 2009-12-30
GENERAL HOSPITAL OF TIANJIN MEDICAL UNIV
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Problems solved by technology

[0003] Although the existing research methods in the study of bone structure are diverse, they all have their own shortcomings: the three-dimensional reconstruction based on CT and MRI can display the arrangement trend of the proximal femoral trabeculae, but due to the different image processing methods, CT and MRI Different sensitivity to bone and soft tissue and other reasons limit the clear display of the microstructure of bone trabecula
However, at present, micro-CT is mainly used in the research of biopsy specimens and small animals. Since it can only scan a small area of ​​interest, a limited range of data can be obtained.
At the same time, the X-ray irradiation necessary to obtain high resolution also limits its application in the human body.

Method used

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  • Method for making three-dimensional visualization model of internal structure of bone
  • Method for making three-dimensional visualization model of internal structure of bone
  • Method for making three-dimensional visualization model of internal structure of bone

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Embodiment 1

[0019] 1. The present invention selects the side femur of a female corpse who died of cardiovascular disease to prepare a dry bone, and vertically cuts a 150 mm long specimen at the proximal end of the femur, and measures its appearance parameters.

[0020] 2. Take a rectangular polymethyl methacrylate box with a side length of 120 mm and a height of 250 mm as the dry bone specimen container, and the lower part of the dry bone specimen container is fixed on the cast iron base by bonding and Kirschner wires. That is, use chloroform to make an adhesive, firmly bond the bottom of the box body on the square cast iron block with the same cross section, and simultaneously punch holes between the bottom of the box body and the cast iron block (such as 1-3 pieces) of Kirschner wires with a diameter of 2mm to strengthen the fixation. Kirschner wires used for internal fixation in orthopedics generally have a diameter of 0.5-2 mm and a length of about 20 cm. The present invention uses a...

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Abstract

The invention is a method for making a three-dimensional visualization model of the internal structure of bone. In the method, a dry bone specimen is embedded and fixed by transparent polymethyl methacrylate (PMMA) to form a model specimen, and then the cross-section of the specimen is ground layer by layer, two-dimensional grayscale images and true color images are scanned and recorded layer by layer, and then three-dimensional medical reconstruction software is used to obtain high-precision three-dimensional visual model of a proximal bone structure. The invention can be applied to three-dimensional reconstruction of bones of human bodies and animals, thereby obtaining the high-precision three-dimensional visual model which can objectively, truly and completely reflect the proximal bone structure. The method can carry out certain evaluation on the structural form of bone trabecula as well as the connectivity of three-dimensional bone trabecular, and can determine the structural parameters of bone trabecular, thus providing scientific basis for medical research and clinical care.

Description

【Technical field】 [0001] The invention relates to a method for making a bone internal structure model, in particular to a method for making a digitized three-dimensional visualization model of the bone internal structure. 【Background technique】 [0002] Trabecular bone, located at the ends of long bones such as the femur and in cubic bones such as the spine, is the major biological tissue-carrying tissue in the human skeleton. Due to the complexity of the force of this type of bone, such as the femur, and the anisotropy of cancellous bone, its special intraosseous structure is formed. The intraosseous structure of the femoral head and femoral neck interweaves into a network of dense lamellae arranged in an orderly manner, and forms five groups: main pressure trabeculae, main force trabeculae, secondary pressure trabeculae, secondary tension trabeculae, and greater trochanteric trabeculae Trabecular. The arrangement direction of the trabeculae is mainly along the principal ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T17/00
Inventor 马信龙马剑雄付鑫孙晓雷赵永涛张清功王晨光
Owner GENERAL HOSPITAL OF TIANJIN MEDICAL UNIV
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