Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition promoting growth of eyelashes or eyebrows

A composition, eyebrow technology, applied in the field of promoting the growth of eyelashes or eyebrows, can solve problems such as side effects

Inactive Publication Date: 2010-03-03
杨雪
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] It is well known that many synthetic prostaglandin analogues such as bimatoprost, latanoprost, travoprost and unoprostone have been widely used to reduce glaucoma patients and ocular hyperplasia. ocular hypertension in hypertensive patients, but they all have similar side effects (Reference 1: Hollo, G. Expert Opin. DrugSaf. 6:45, 2007), the most common adverse reaction of these synthetic prostaglandin analogs is conjunctival hyperemia

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition promoting growth of eyelashes or eyebrows

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Emulsion

[0028] The specific content of the active ingredients of the compound cosmetic is as follows: timolol maleate (0.70%, w / v; equivalent to timolol 0.50%, w / v) and evening primrose oil (70%, w / v).

[0029] The compound timolol and evening primrose oil is an inverse emulsion, and SPAN-40 and SPAN-60 are solubilizing stabilizers. See the table below for compound combinations. Dissolve 70g of timolol maleate in 1649mL of purified water, and then slowly pour the aqueous solution into a mixture containing 7000g of evening primrose oil, 70g of SPAN-40 and 30g of SPAN-60 under vigorous stirring. The obtained emulsion was mechanically stirred for 10 minutes until the emulsion was uniform and stable (final volume 10 L).

[0030] Element

Embodiment 2

[0032] Liquid

[0033] The specific content of the active ingredients of the compound cosmetic is as follows: timolol maleate (2.8%, w / v; equivalent to timolol 2.0%, w / v) and black currant oil (1.0%, w / v).

[0034] The compound timolol and blackcurrant oil is an aqueous solution preserved aseptically, and the compound combination is shown in the table below: the compounding method is based on timolol eye drops, which contains an isotonic phosphate buffer system at pH 6.7 ; The compound preservative is indica ethyl ammonium chloride with a concentration of 200ppm. Polysorbate 80 is a co-solvent.

[0035]

Embodiment 3

[0037] cream

[0038] A topical cream containing timolol (0.5%, w / v) and evening primrose oil (5.0%, w / v) is prepared as follows:

[0039] Under nitrogen protection, place 50g timolol, 500g evening primrose oil, 20g sorbitan oleate, and 2780mL (2500g) medium-chain triglycerides in a stainless steel container, and stir evenly at 60-65°C until The drug is completely dissolved. Then add 20g of Carbomer 1342 NF and 100g of Carbomer 934P into the above drug mixture and stir until the polymers are completely mixed. Under the protection of nitrogen, increase the mixing and stirring speed, and stir for another 5 minutes to prepare mixture A. In addition, 5.0 g of disodium edetate, 10 g of sodium subsulfite heptahydrate and about 6.3 L of purified water were mixed until completely dissolved (stirring for about 10 minutes) to prepare mixture B. Then slowly add the mixture B to the mixture A containing the drug and the high molecular polymer. Under nitrogen protection, stir evenly at...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a novel composition containing timolol and essential oil for promoting the growth of eyelashes or eyebrows, cosmetics containing the composition, and application of the composition for promoting the growth of the eyelashes or the eyebrows.

Description

technical field [0001] The present invention relates to a novel composition for promoting growth of eyelashes or eyebrows containing timolol and essential oil as active ingredients, a cosmetic containing the composition, and an application of the composition for promoting growth of eyelashes or eyebrows. Background technique [0002] It is well known that many synthetic prostaglandin analogues such as bimatoprost, latanoprost, travoprost and unoprostone have been widely used to reduce glaucoma patients and ocular hyperplasia. ocular hypertension in hypertensive patients, but they all have similar side effects (Reference 1: Hollo, G. Expert Opin. DrugSaf. 6:45, 2007), the most common adverse reaction of these synthetic prostaglandin analogs is conjunctival hyperemia . [0003] In a one-year randomized double-blind safety and efficacy evaluation trial, glaucoma patients were divided into 3 groups: Lubigan 0.03% once a day, (n=474); Lubigan 0.03% twice a day (n=474); =483); t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/60A61K8/97A61K8/49A61Q1/10A61Q7/00A61P17/14
Inventor 杨雪
Owner 杨雪
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com