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Body-weight maintenance and body composition

A body and individual technology, applied in the direction of organic active ingredients, drug combinations, food ingredients, etc., can solve problems such as weight gain

Inactive Publication Date: 2010-06-09
DSM IP ASSETS BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The risk of losing weight rapidly and then not maintaining the lost weight is the so-called "yo-yo" diet, the consequence of which is further weight gain

Method used

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  • Body-weight maintenance and body composition
  • Body-weight maintenance and body composition
  • Body-weight maintenance and body composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0104] Fabuless TM lotion

[0105] A 40 wt% emulsion was prepared with rectified palm oil (batch size 300 g).

[0106]

[0107] Palm oil was melted at 50°C and mixed with rectified oat oil. The oil phase and water were preheated to 65-70°C, then the oil phase was added to the water with high shear mixing at 15,000 rpm over a period of 4 minutes. The pre-emulsion was then divided into two parts; one was homogenized at 400 bar and the other at 800 bar, both at 60°C for 6 cycles (Rannie Homogenizer, Model Mini-Lab 8.30H, APV Rannie ,Denmark).

[0108] Both parts prepared yielded emulsions of similar creamy consistency. The average particle size (Z-mean) in both cases was around 480 nm (Zetasizer 4, Malvern Instruments, UK).

[0109] The emulsion prepared as above (hereinafter referred to as Fabuless TM and marketed by DSM Food Specialties, Delft, The Netherlands) can be stored at 2-8°C until used as an ingredient in the manufacture of the product.

Embodiment 2

[0111] A study of weight maintenance after a period of weight loss

[0112] introduction

[0113] Conduct studies to investigate consumption with or without Fabuless TM Effects of dietary replacement products on weight maintenance and body composition.

[0114] The main purpose is to determine the content of Fabuless TM The effect of a meal replacement product on weight maintenance, which was determined at the time of consumption without Fabuless TM But a meal replacement product with the same fat content was carried out after 12 weeks.

[0115] The secondary objective is to determine the presence or absence of Fabuless TM Meal replacement effects on:

[0116] - fat mass, fat-free mass and bone mass;

[0117] - waist and hip circumference;

[0118] - Body temperature and sagittal measurement;

[0119] - blood pressure and pulse rate; and

[0120] -safety.

[0121] Research design

[0122] The study was a randomized, double-blind, placebo-controlled parallel de...

Embodiment 3

[0191] Additional Statistical Analysis of Caliper Measurements

[0192] Further statistical analysis was performed on skinfold thickness data measured by calipers, a previously established method for calculating body composition. This evaluation was performed at baseline and after 4, 8 and 12 weeks of treatment, and according to Durnin and Wormersly (Brit J. Nutr. (1974) 32 , 77) to calculate body fat mass.

[0193] Statistical evaluations were performed using analysis of variance (ANOVA). The reduction in body fat mass was significantly greater in the active group than in the placebo group, p=0.0108 (see Table 13).

[0194] sheet

[0195] Table 1. Timeline of events

[0196]

[0197] 1 The research nurse will ask the subject if he / she knows this information.

[0198] 2 Co-administration will be known in Observation 1.

[0199] Table 2. Summary results of anterior-posterior measurements and body weight for each treatment. Subjects 1006 and 1036 were excluded. ...

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PUM

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Abstract

Use of a mixture comprising a triglyceride oil having a solid fat content at ambient to body temperature and an emulsifier for the preparation of a pharmacologically active composition for increasing body fat mass loss or maintaining blood pressure in an individual. Such use may be carried out subsequent to a period of weight loss.

Description

technical field [0001] The present invention relates to the field of body weight maintenance, more particularly to the field of long-term body weight maintenance in humans. Accordingly, the present invention relates to enhancing body fat mass loss and maintaining blood pressure. Background of the invention [0002] The increasing incidence of obesity is a recognized medical problem in developed countries. Obesity is a major factor in a number of diseases, including coronary heart disease, hypertension, non-insulin-dependent diabetes mellitus, pulmonary dysfunction, osteoarthritis, and certain types of cancer. Obesity occurs when the balance between energy intake and energy expenditure shifts towards a positive energy balance. [0003] Obesity can be classified as a mild condition (20-30% overweight), moderate condition (30-60% overweight) or severe condition (>60% overweight). Obesity comes with numerous health risks. It can impair heart and lung function, disrupt end...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23D7/005A23D9/007A23L1/29A23L1/30A61K31/7032A61P3/40A61P3/06A61P9/12C11C3/00A23L33/00
CPCA23D7/0053A23D7/011A23V2002/00A23D7/013A61K31/7032A23L1/3008A23L1/296A23L1/3006A23D7/001A23D7/003A23L33/40A23L33/115A23L33/12A61P3/00A61P3/04A61P3/06A61P9/00A61P9/12A23V2200/332A23V2250/194A23V2250/1842A23V2200/222
Inventor 本格特·赫斯勒夫安尼卡·韦比尔格
Owner DSM IP ASSETS BV