Nano-scale pine bark extract and preparation method thereof

A pine bark extract and nano-scale technology, which is applied in the ingredients of cosmetics and the field of medicine, can solve the problems of reducing the degradation of anthocyanins, achieve the effects of improving immunity, fine particle size, and regulating human immune function

Active Publication Date: 2010-06-30
钱娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the deficiencies in the prior art, aiming at the excessive particle size of the pine bark extract in the prior art, which is difficult to be quickly absorbed by the human body, a new nanoscale pine bark extract preparation method is provided to improve Active ingredients of pine bark extract, and reduce or slow down the degradation of anthocyanins, to obtain a high-purity pine bark extract with good solubility, good stability, low viscosity, fine particle size and easy absorption by the human body. The active ingredient can reach more than 99%

Method used

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  • Nano-scale pine bark extract and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The following is a non-limiting example preparation method of nanoscale pine bark extract:

[0039] (a) Raw material processing: the collected pine needles and pine bark are shortened, sorted, and washed with deionized water.

[0040] (b) Filtrate extraction treatment: put the raw materials into an extraction tank, add 10 times the amount of water as an extraction solvent, the extraction temperature is 80 degrees Celsius, and the extraction time is 8 hours.

[0041] (c) Concentration treatment: the obtained extract is introduced into a vacuum concentrator for recovery under reduced pressure, the temperature is 80 degrees Celsius, the vacuum degree is 0.10, and the ratio of the concentrated solution to the raw material is 1:2.

[0042] (d) High-efficiency countercurrent extraction treatment: put the concentrated solution into the extraction tower, extract twice with ethyl acetate as an organic solvent, the dosage is 2 times, and the number of cycles is 4 to 5 times, and ...

Embodiment 2

[0052] Effectively detect the active ingredients and safety of the extract below in conjunction with this embodiment:

[0053] In this experiment, the phenolic hydroxyl group existing in the molecular structure of proanthocyanidins is used for inspection, because proanthocyanidins can react with copper acetate complex precipitation agent in neutral medium to produce insoluble brown-yellow precipitates, which are determined by atomic absorption method after centrifugation. Excessive Cu2+ in the serum, so that an indirect method for the determination of the effective components of proanthocyanidins can be established. The detection method has the advantages of simplicity, rapidity, and less reagent consumption, and is used for the determination of actual samples with accurate results.

[0054] Test instruments and reagents:

[0055] Adopt TAS-986 atomic absorption spectrophotometer (Beijing General Analysis General Instrument Co., Ltd.); copper hollow cathode lamp (Shanghai Dia...

Embodiment 3

[0072] (1) the purposes of described nanoscale pine bark extract as additive in skin care cosmetics:

[0073] The nanoscale pine bark extract obtained by the above preparation method is used as an additive to add to the matrix, the extract accounts for 0.1% to 80% of the total weight, and is suitable for skin care cosmetics. The matrix can be in any form of liquid, solid, emulsion, or paste.

[0074] A. The formula of anti-aging whitening and speckle-removing skin care gel

[0075] Use 10G nanoscale pine bark extract, 0.5G carbomer, 1G sweet almond oil, 0.5ML antibacterial agent, 0.5G antioxidant, add 10ML rose hydrosol, and add distilled water to the rest to 100ML, mix and stir well to make an antibacterial Aging whitening anti-wrinkle skin care gel.

[0076] Compared with traditional whitening and speckle-removing products: this product uses proanthocyanidins that have been nano-sized and effective up to 99%, so it is easier to be directly absorbed by the human body, and g...

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Abstract

The invention relates to a method for extracting nano-scale proanthocyanidin oligomers from pink bark. The production technical process of the method comprises: raw material treatment, filtrate extraction treatment, concentration treatment, high-efficiency countercurrent extraction treatment, dilution treatment, water dissolution treatment, liquid phase intercalation treatment, nano crushing treatment, drying and depolymerization treatment, purification treatment and sterilization and packing treatment. In the method, water is used as an extraction solvent, ethyl acetate is used as an extraction solvent, and after weakly acidic electrolyzed distilled water is mixed, a nanocrystallization process is used to prepare a finished product. The countercurrent electrolysis extraction method has high extraction rate and low cost, effectively separates the proanthocyanidin oligomers from proanthocyanidin polymers, greatly improves product extraction yield and quality, improves OPC active ingredient content to over 99 percent and effectively solves the technical problem of difficult direct absorption by human bodies, which is caused by large proanthocyanidin particle size and low active ingredient content. The invention also provides a nano-scale pine bark extract prepared by the method.

Description

technical field [0001] The invention relates to the fields of natural products and food additives, in particular, anthocyanins extracted from pine bark are used as raw materials of health food, or used as additives in various fields such as ingredients of medicine and cosmetics. Background technique [0002] Extracts from the bark of French maritime pine and other species of pine contain proanthocyanidins, powerful antioxidants. The pine bark extract contains a variety of amino acids. A large number of scientific researches at home and abroad have confirmed that the proanthocyanidins extracted from the pine bark are the most powerful and effective anti-aging substances found so far, which can improve the inferiority complex of modern people. Health status, so that more people live a long and healthy life. [0003] Proanthocyanidin substances are polymerized by different numbers of flavan-3-ols or flavan-3,4-diols, and 2-4 polymers are called oligomeric proanthocyanidin Olig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07G99/00A23L1/28A23L1/29A23L1/30A61K8/97A61Q19/08A61Q19/00A61K36/15A61P37/02A61P39/06A61P17/18A23L31/00A23L33/105A61K8/9767
Inventor 钱娟
Owner 钱娟
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