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Method and device for real-time observation of cells in incubator based on optical fiber image transmission

A real-time observation and incubator technology, which is applied in measuring devices, signal transmission systems, and material analysis through optical means, can solve problems such as observations that are not suitable for cell morphology, and achieve high-fidelity images, wide application range, and wide field of view. wide effect

Inactive Publication Date: 2011-12-07
SOUTH CHINA UNIV OF TECH
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Problems solved by technology

However, due to the detection principle based on laser (coherent light) interference optics and the inability to make small movements (like a microscope), this detector is not suitable for the observation of cell morphology

Method used

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  • Method and device for real-time observation of cells in incubator based on optical fiber image transmission
  • Method and device for real-time observation of cells in incubator based on optical fiber image transmission
  • Method and device for real-time observation of cells in incubator based on optical fiber image transmission

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Embodiment Construction

[0028] The present invention will be further described below in conjunction with the drawings and embodiments, but the protection scope of the present invention is not limited to the range described in the embodiments.

[0029] like figure 1 As shown, the real-time observation device for cells in the incubator based on optical fiber image transmission includes an objective lens 1, a displacement fine-tuning device 2, an optical fiber image transmission bundle 3, an eyepiece 4, a CCD camera 5, a light source beam expander 6, a transmission beam 7, a computer 8, The first wireless transceiver module 9, the light source 10, the second wireless transceiver module 11, the transparent cell culture box 12 and the cell culture box 13; the transparent cell culture box 12 is positioned in the cell culture box 13, and the objective lens 1 is positioned at the transparent cell culture box 12 front end, the front end of the optical fiber image transmission bundle 3 is connected to the obje...

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Abstract

The invention discloses a method and a device for real-time observation of cells in an incubator based on optical fiber image transmission. The transparent cell culture box of the device is located in the cell culture box, and the objective lens is located at the front end of the transparent cell culture box. Located at the rear end of the mirror, it is connected to the second wireless transceiver module; the computer is connected to the first wireless transceiver module, and the first wireless transceiver module is connected to the second wireless transceiver module for signals. The present invention can observe the cells in the incubator conveniently and flexibly, without taking the living cells out of the incubator to observe by the endpoint method, but can observe in real time in the incubator, which provides convenience for the observation and analysis of cell culture It is a fast method, and at the same time, the whole process of cell culture can be observed through the device, which greatly improves the efficiency and quality of the whole cell culture.

Description

technical field [0001] The invention relates to a cell observation method and device, in particular to a method and device for real-time cell observation in an incubator based on optical fiber image transmission. Background technique [0002] Since the current cell culture must be cultured in an incubator, this brings inconvenience to the real-time observation of cells. However, cell culture is a key part of many biomedical experiments, and the quality of cell culture will affect the progress of subsequent experiments. With the development and needs of biomedical research, people have increasingly strong requirements for real-time observation of cell culture, because the significance of real-time observation of cells to biomedical research is becoming more and more important. [0003] The existing observation of cells in the incubator is to move the cultured cells out of the incubator, and then observe the culture state of the cells under a microscope. This endpoint method...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/84G01N21/01G08C17/02
Inventor 史景伦张荣锋韦岗熊尚坤
Owner SOUTH CHINA UNIV OF TECH
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