Application of starfishes to preparation of medicament for treating osteoporosis

An osteoporosis, starfish technology, applied in drug combinations, bone diseases, pharmaceutical formulations, etc., can solve problems such as increasing endometrial cancer, and achieve the effect of increasing osteoblast growth, low cost, and quick effect

Active Publication Date: 2010-08-18
大连美罗中药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

What needs to be mentioned is that estrogen replacement therapy used to be the first choice for the treatment of postmenopausal osteoporosis in women, but new research shows that long-term use of estrogen may cause endometrial and mammary gland hyperplasia, and increase the occurrence of endometrial cancer and mammary gland hyperplasia. cancer risk

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1: the capsule for the treatment of osteoporosis is prepared as a raw material with starfish (Roche sea plate car)

[0026] ①Take 300g of Roche sea pan with a water content of 3%, and steam it with circulating steam for 2 hours;

[0027] ②Dry at 60°C until the water content is less than 7%, take it out, and place it at room temperature at room temperature 20±2°C and relative humidity 45%-65%;

[0028] ③Crush and pass through a 100-mesh sieve;

[0029] ④Pack it into capsules and make 1000 capsules in total.

[0030] The starfish capsule of this embodiment is used as a medicine for treating osteoporosis, and it is administered orally. The daily dosage for adults is 4-10 capsules, divided into two doses; the course of treatment is 4-6 weeks.

Embodiment 2

[0031] Embodiment 2: take starfish (Dow's sun starfish) as raw material to prepare the pill for the treatment of osteoporosis

[0032] ①Take 30g of Dow Sun Starfish with a water content of 6%, and steam it with circulating steam for 3 hours;

[0033] ②Dry at 70°C until the water content is less than 7%, take it out, and place it at room temperature at room temperature 22±2°C and relative humidity 45%-65%;

[0034] ③ pulverize and pass through a 140-mesh sieve;

[0035] ④ Use 25g of refined honey to add appropriate amount of water pan pills and dry to make 500 water honey pills.

[0036] The starfish water honey pill of this embodiment is used as a medicine for treating osteoporosis, and it is administered orally. The daily dosage for adults is 20-50 pills, divided into two doses; the course of treatment is 4-6 weeks.

Embodiment 3

[0037] Embodiment 3: take the starfish (Porphyllum spinacha) as raw material to prepare the pill for the treatment of osteoporosis

[0038] ①Take 30g of sea spinach with a water content of 8% and steam it with circulating steam for 4 hours;

[0039] ②Dry at 80°C until the water content is less than 7%, take it out, and place it at room temperature at 24±2°C and relative humidity of 45%-65%;

[0040] ③ pulverize and pass through a 180-mesh sieve;

[0041] ④ Use 25g of refined honey to add appropriate amount of water pan pills and dry to make 500 water honey pills.

[0042] The starfish water honey pill of this embodiment is used as a medicine for treating osteoporosis, and it is administered orally. The daily dosage for adults is 20-50 pills, divided into two doses; the course of treatment is 4-6 weeks.

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PUM

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Abstract

The invention discloses the application of starfishes to the preparation of a medicament for treating osteoporosis. The application of the starfishes is realized by steaming, drying, cooling and crushing Chinese medical starfish herbs, such as asterias rollestoni and asterias amurensis from asteriidae animals or Dow sun starfish from solasteridae animals, preparing and orally administrating. Proved by research, the starfishes have the functions of stimulating the growth of sclerotomal cells, promoting the pigmentation, enhancing the bone density, and the like and have remarkable effect of treating the osteoporosis. The medicament for treating osteoporosis, which is prepared by the technical scheme, has the advantages of good treatment, high effect taking, high curative effect without any side effect, and the like during clinical applications and has sufficient drug resources, simple preparation method and low cost.

Description

technical field [0001] The invention relates to the new application of the traditional Chinese medicine starfish, especially the application in preparing medicine for treating osteoporosis. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by decreased bone mass and degeneration of bone microstructure. The clinical manifestations are increased bone fragility, which greatly increases the risk of fracture, even with minor trauma. Fractures are also prone to occur in the absence of trauma. [0003] There are 200 million osteoporosis patients in the world, the incidence of osteoporosis is higher in the elderly, and there are more women than men. According to the standards of the World Health Organization, the results of the National Health and Nutrition Survey in the United States show that osteoporosis seriously affects the quality of life of the elderly. Among people over the age of 50, 1 / 2 of women and 1 / 5 of men will develop osteoporosi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/56A61P19/10A61K35/616
Inventor 张成海周文波石桂芳姜伟
Owner 大连美罗中药厂有限公司
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