Injection containing ibuprofen and preparation method thereof

A technology for injection and water for injection, applied in the field of pharmacy, can solve problems such as difficult development, and achieve the effects of reducing irritation, enhancing stability and improving safety

Inactive Publication Date: 2010-08-25
FANTAI INST OF CHEM MEDICINES NANJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, some formulations of ibuprofen, especially oral or injectable, are difficult to develop

Method used

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  • Injection containing ibuprofen and preparation method thereof
  • Injection containing ibuprofen and preparation method thereof
  • Injection containing ibuprofen and preparation method thereof

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Abstract

The invention provides an injection containing ibuprofen and a preparation method thereof. The injection has the advantages of good stability, high safety and good treatment effect. The injection contains ibuprofen and arginine, wherein the molar ratio of the arginine to the ibuprofen is larger than or equal to 1 to 1.

Description

technical field The invention belongs to the field of pharmacy, and relates to an injection containing ibuprofen and a preparation method thereof. Background technique Ibuprofen (Ibuprofen), is the first alkylphenylpropionic acid non-steroidal anti-inflammatory drug in clinical application, its structure is as follows: Since it was developed in 1964, ibuprofen has been widely used for anti-inflammatory, analgesic, antipyretic, anti-rheumatic and so on. Because ibuprofen will produce gastrointestinal adverse reactions common to non-steroidal anti-inflammatory drugs, and its biological half-life is short, frequent medication is required to maintain the therapeutic concentration, thus further increasing the gastrointestinal reactions of the drug, such as abdominal distension , indigestion, nausea, vomiting, diarrhea, peptic ulcer, etc., even lead to gastrointestinal bleeding, and also increase the damage to the kidneys, so people have been devoting themselves to research on n...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/192A61K47/16A61P29/00
Inventor 涂家生吴建梅嵇元欣刘实董少华
Owner FANTAI INST OF CHEM MEDICINES NANJING
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