Tool and method for diagnosing premature rupture of membrane by continuous monitoring
A diagnostic tool and technology for premature rupture of membranes, applied in biological testing, material inspection products, etc., can solve the problems of inaccurate and invasive diagnostic methods, inability to perform continuous real-time monitoring, etc., and achieve easy operation, avoid false negatives, and sensitivity and highly specific effects
Active Publication Date: 2014-05-14
顾瑜
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[0007] In summary, currently commonly used diagnostic methods are either inaccurate, highly invasive, or both, and neither continuous real-time monitoring
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[0025] like figure 1 or figure 2 A continuous monitoring premature rupture of membranes diagnostic tool shown is divided into three layers, the upper isolation filter layer 2 is a translucent polymer microporous filter membrane that can filter and isolate macromolecular urine protein; the lower absorption layer 5, Contains superabsorbent resin and leak-proof film that can absorb excess leakage liquid, adhesive tape and release paper on the back of the lower layer; the test system in the middle layer consists of a type A solid phase carrier 3 containing enzyme liquid and PH indicator and It is composed of B-type solid-phase carrier 4 containing a pH indicator. The edges of the upper and lower layers are heat-compressed and bonded, and the middle layer is fixed in the middle and cannot slide arbitrarily. The A-type solid phase carrier 3 and the B-type solid phase carrier 4 are placed in a non-contact up and down overlap ( figure 1 ) or placed left and right ( figure 2 ), in...
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The invention relates to a tool and a method for diagnosing premature rupture of a membrane by continuous monitoring, which are applicable to household. The tool consists of an upper isolation filter layer, a medium testing system and a lower absorption layer, wherein the testing system consists of an A-type solid-phase vector containing urease and pH indicator and a B-type solid-phase vector containing the pH indicator. The diagnosing method comprises the following steps that: when fluid from the lower body simultaneously soaks two solid-phase vectors, and color development on the A-type solid-phase vector and the B-type solid phase vector has differences, the fluid is urine; and when the color development and color gradation on the A-type solid-phase vector and the B-type solid-phase vector are completely same, the fluid is amniotic fluid. The tool and the method have the advantages of simple operation, higher sensitivity and specificity, continuous detection of discontinuous leakage of the amniotic fluid and real-time property.
Description
Technical field: [0001] The invention relates to a non-invasive continuous monitoring premature rupture of membranes diagnostic tool and a diagnostic method suitable for home use. Background technique: [0002] Premature rupture of membranes (PROM) is defined as the rupture of membranes before labor, and its incidence rate is 2.7%-17%. Premature rupture of membranes can induce premature labor and increase the chance of intrauterine infection and puerperal infection. For those who gave birth 48 hours after rupture of the membranes, the maternal infection rate was 5%-20%, the sepsis rate was 1:145, and the maternal mortality rate was 1:5500. Fetal aspiration of infected amniotic fluid can cause pneumonia and fetal distress. Increased chance of umbilical cord prolapse. The closer to the full term of pregnancy, the higher the rate of labor signs after rupture of the membranes. [0003] Although early detection of premature rupture of membranes has very important clinical sig...
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IPC IPC(8): G01N33/84G01N33/52
Inventor 王润顾瑜
Owner 顾瑜