Medicine composite for treating cervical erosion and preparation method thereof

A technology of cervical erosion and its composition, which is applied in the field of medicine, can solve the problems of unsatisfactory treatment of cervical erosion, and achieve the effects of simple preparation method, convenient use, and improved curative effect

Active Publication Date: 2010-09-15
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, existing drugs are still unsatisfa

Method used

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  • Medicine composite for treating cervical erosion and preparation method thereof

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preparation example Construction

[0031] The preparation method of the above-mentioned pharmaceutical composition for the treatment of cervical erosion comprises the following steps:

[0032] 1. Preparation of Periplaneta americana extract:

[0033] a, coarse crushing: the dried Periplaneta americana is pulverized to obtain the Periplaneta americana meal;

[0034] b. Soaking: Add 3 to 5 times the amount of water to the coarse powder in step a, and soak for 0.5 to 2 hours to obtain a coarse powder mixture. The soaking temperature is 70°C to 78°C. The method carried out three extractions to obtain the extract;

[0035] c. Three extractions: extract the coarse powder mixed liquid for the first time, and the extraction time is 7 to 9 hours; then add water 2 to 4 times the amount of the remaining liquid to the remaining liquid after the first extraction, and then carry out the second extraction. The first extraction, the extraction time is 5 to 7 hours; finally, add 2 to 4 times the amount of water to the residua...

Embodiment 1

[0048] The adopted formula is: 100 parts of Periplaneta americana extract; 100 parts of pomegranate peel; 70 parts of citric acid.

[0049] The preparation method is: coarsely crush the dried Periplaneta americana, add 300Kg water for every 100Kg coarse powder, soak for 0.5 hours, the temperature is about 70°C, extract three times, the first time is 7 hours; the second time add 200Kg water, extract for 5 hours ; Add water 200Kg for the third time and extract for 3 hours. Combine three extracts, filter, and when the filtrate is concentrated to a relative density of 1.05 (70°C), add ethanol with a concentration of 93% w / w to make the alcohol content 45%, keep stirring at 70°C for 20 minutes, and let it stand for 10 minutes. After 1 hour, discard the upper layer of grease, filter the lower layer of medicinal liquid, and reclaim ethanol from the filtrate, and concentrate under reduced pressure to a relative density of 1.20 (70° C.), and concentrate to the ointment of moisture≤25% ...

Embodiment 2

[0051] The adopted formula is: 100 parts of Periplaneta americana extract; 180 parts of pomegranate peel; 120 parts of citric acid.

[0052] The preparation method is: coarsely crush the dried Periplaneta americana, add 500Kg of water to every 100Kg of coarse powder, soak for 2 hours, the temperature is about 78°C, extract three times, the first time is 9 hours; the second time add 400Kg of water, extract for 7 hours ; Add water 400Kg for the third time and extract for 5 hours. Combine three extracts, filter, and when the filtrate is concentrated to a relative density of 1.25 (90°C), add ethanol with a concentration of 97% w / w to make the alcohol content 55%, keep stirring at 90°C for 40 minutes, and let it stand for 14 After 1 hour, discard the upper layer of grease, filter the lower layer of liquid medicine, and reclaim ethanol from the filtrate, and concentrate under reduced pressure to a relative density of 1.25 (90° C.), and concentrate to the ointment of moisture≤35% und...

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Abstract

The invention discloses a medicine composite for treating cervical erosion and a preparation method thereof. The medicine composite mainly comprises a mixture of active ingredients prepared from periplaneta Americana extract, pomegranate peel and citric acid, and the active ingredients are in the following proportion by weight: 100 parts of periplaneta Americana extract, 1-180 parts of pomegranate peel and 1-200 parts of citric acid. The preparation method of the medicine composite for treating cervical erosion comprises the following steps of: extracting the periplaneta Americana extract, extracting active ingredients of the pomegranate peel, mixing the extracted ingredients, and then adding in citric acid for preparing the medicine composite. In the invention, the medicine composite has simple preparation method, gives full play to the function of the periplaneta Americana extract, effectively improves the curative effect on the cervical erosion, is convenient to use, has tiny toxic and side effects, and is a new medicament worthy of generalization.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating cervical erosion and a preparation method thereof. Background technique [0002] According to literature records, Periplaneta americana is the largest insect in the cockroach family. It is native to South America. Periplaneta americana is a traditional Chinese medicinal material. It is used as medicine with dried and fresh adults. Its nature is salty, poisonous and pungent. , has the functions of dispelling blood stasis, eliminating stagnation, detoxification, diuresis, and detumescence; it is mainly used to treat children with malnutrition, tonsillitis, body mass, carbuncle sores, and centipede and snake bites. [0003] In recent years, with the continuous development of science and technology, after years of research, it has been found that the epidermis of Periplaneta americana contains sclera and chitin, bromine, zinc, nickel, mangan...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K36/888A61P15/00A61K31/194A61K35/64
Inventor 耿福能刘彬黄婉怡胡若瑛杜江
Owner SICHUAN GOODDOCTOR PANXI PHARMA
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