Medicinal composition for treating hypertension left ventricular hypertrophy and preparation method thereof

A composition and technology of the left ventricle, applied in the field of Chinese patent medicine, achieves the effect of moderate price, simple preparation process, and easy-to-obtain materials

Inactive Publication Date: 2010-11-17
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this medicine belongs to the compound preparation of western medicine, and the compound preparation of traditional Chinese medicine in hypertensive left ventricular hypertrophy has not been reported yet, so the present invention belongs to the first Chinese medicine compound preparation in China

Method used

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  • Medicinal composition for treating hypertension left ventricular hypertrophy and preparation method thereof
  • Medicinal composition for treating hypertension left ventricular hypertrophy and preparation method thereof
  • Medicinal composition for treating hypertension left ventricular hypertrophy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0079] Example 1: Granules

[0080] Prescription: Astragalus 30g, Fangji 10g, Panax notoginseng 15g, Salvia miltiorrhiza 15g, Wood beetle 10g, Trichosanthes 10g, Uncaria 10g, Gastrodia elata 10g

[0081] Preparation method: extract the raw material medicine with water for 3 times according to the above ratio, add 10 times of water each time and decoct for 3 hours, then combine the decoction solution, filter, and finally concentrate the filtrate to an extract with a relative density of 1.50, first press the immersion Add 4 times the weight of dextrin to the weight of the paste, vacuum-dry at 80°C, pulverize through a 65-mesh sieve to obtain a dry powder, then add 2 times the weight of powdered sugar according to the weight of the dry powder, and use 95% ethanol as a wetting agent to make a soft material. Granulate with a 16-mesh sieve, dry, granulate, and pack into 10g packs.

[0082] Dosage: 10g each time, 2 times a day, take it with warm water.

example 2

[0083] Example 2: Tablet

[0084] Prescription: Astragalus 20g, Fangji 10g, Panax notoginseng 15g, Salvia miltiorrhiza 20g, Wood beetle 25g, Trichosanthes 16g, Uncaria 12g, Gastrodia elata 7g

[0085] Preparation method: extract the raw material medicine with water for 3 times according to the above ratio, add 12 times of water each time and decoct for 1 hour, then combine the decoction solution, filter, and finally concentrate the filtrate to an extract with a relative density of 1.49, first press the immersion Add 4 times the weight of dextrin to the weight of the paste, vacuum-dry at 80°C, pulverize through a 65-mesh sieve to obtain a dry powder, then add 2 times the weight of powdered sugar according to the weight of the dry powder, and use 95% ethanol as a wetting agent to make a soft material. Granulate with a 16-mesh sieve, dry, and compress into tablets by conventional methods to make tablets.

[0086] Dosage: Take orally, 4 tablets at a time, 2 times a day.

example 3

[0087] Example 3: Capsules

[0088] Prescription: Astragalus 40g, Fangji 20g, Panax notoginseng 8g, Salvia miltiorrhiza 6g, Wood beetle 8g, Trichosanthes 12g, Uncaria 16g, Gastrodia elata 20g.

[0089] Preparation method: Extract the raw material medicine with water according to the above ratio twice, add 8 times of water each time and decoct for 3 hours, then combine the decoction liquid, filter, and finally concentrate the filtrate to an extract with a relative density of 1.12, first press the immersion Add 4 times the weight of dextrin to the weight of the paste, vacuum-dry at 80°C, pulverize through a 65-mesh sieve to obtain a dry powder, then add 2 times the weight of powdered sugar according to the weight of the dry powder, and use 95% ethanol as a wetting agent to make a soft material. Granulate with a 16-mesh sieve, dry, granulate, and pack into gelatin capsules to make capsules.

[0090] Dosage: Take orally, 4 capsules at a time, 2 times a day.

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Abstract

The invention relates to a Chinese patent medicament taking plants as raw materials, in particular to a medicinal composition for treating hypertension left ventricular hypertrophy, which consists of active ingredients and pharmaceutically-acceptable auxiliary materials. The medicinal composition is characterized in that the active ingredients are prepared from the following raw material medicaments in percentage by weight: 15 to 50 percent of astragalus, 10 to 20 percent of yellowmouth dutchmanspipe root, 5 to 25 percent of notoginseng root, 5 to 25 percent of root of red-rooted salvia, 5 to 25 percent of ground beeltle, 5 to 20 percent of snakegourd fruit, 5 to 20 percent of gambir plant and 5 to 20 percent of tall gastrodia tuber. By combining the medicaments of the medicinal composition according to a formula, the medicinal composition has the effects of replenishing qi and invigorating blood circuit and reducing phlegm and calming the liver, and has the advantages of readily available medicinal materials and moderate cost.

Description

field of invention [0001] The invention relates to a medical preparation, in particular to a Chinese patent medicine with plants as raw materials. Background technique [0002] Essential hypertension, namely hypertension (EH), is an independent disease whose main clinical manifestation is increased blood pressure, the cause of which is not yet clear. In the past 20 years, with the development of cardiovascular molecular biology and the development of large-scale antihypertensive clinical trials, the traditional understanding of hypertension has been updated. Hypertension leads to structural and functional changes in the cardiovascular system, namely left ventricular hypertrophy (LVH) caused by hypertension. In recent years, the prevalence of essential hypertension in various countries in the world has reached 10%-20%, about 1 / 3 of hypertensive patients will have left ventricular hypertrophy, and hypertensive patients with left ventricular hypertrophy have higher cardiovascu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/16A61K9/20A61K9/48A61P9/12A61P9/00A61K35/64
Inventor 袁立霞
Owner SOUTHERN MEDICAL UNIVERSITY
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