Unlock instant, AI-driven research and patent intelligence for your innovation.

Traditional Chinese medicine for treating migraine and preparation method thereof

A technology for migraine and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine for treating migraine and its preparation, can solve the problems of few prescriptions for warming and activating blood circulation, and achieves good therapeutic effect, hypnotic effect and analgesic effect.

Active Publication Date: 2012-01-11
SHANGHAI KAIBAO PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the Chinese patent medicines for treating migraine are based on calming the liver, promoting blood circulation, and expelling wind, and there are few prescriptions for warming and promoting blood circulation.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine for treating migraine and preparation method thereof
  • Traditional Chinese medicine for treating migraine and preparation method thereof
  • Traditional Chinese medicine for treating migraine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The parts by weight of each raw material in the formula of the traditional Chinese medicine for treating migraine described in the embodiment of the present invention are: Chuanxiong 375, Angelica dahurica 375, Evodia rutaecarpa 187 and Menthol 8.3.

[0027] Accurately weigh the weight of each raw material as follows: 375 grams of Rhizoma Chuanxiong, 375 grams of Angelica dahurica, 187 grams of Evodia rutaecarpa and 8.3 grams of menthol; 80% ethanol as a solvent, after soaking for 24 hours, percolate, collect the filtrate, recover ethanol from the filtrate, concentrate to a thick paste, add 1 times the amount of dextrin, mix well, use 95% ethanol as a wetting agent, and make Granules, dry below 60°C, whole grains, and set aside; Evodia rutaecarpa is reflux extracted twice with 70% ethanol, the first time is 2 hours, the second time is 1.5 hours, the decoction is combined, filtered, ethanol is recovered, concentrated to a thick paste, Dry under reduced pressure at a vacu...

Embodiment 2

[0029] The parts by weight of each raw material in the formula of the traditional Chinese medicine for treating migraine described in the embodiment of the present invention are: Rhizoma Chuanxiong 187, Angelica dahurica 187, Evodia 93 and Menthol 4.1.

[0030] Accurately weigh the weight of each raw material as follows: 187 grams of Rhizoma Chuanxiong, 187 grams of Angelica dahurica, 93 grams of Evodia rutaecarpa and 4.1 grams of Menthol; 80% ethanol as a solvent, after soaking for 12 hours, percolate, collect the filtrate, recover ethanol from the filtrate, concentrate to a thick paste, add 1 times the amount of dextrin, mix well, and use 95% ethanol as a wetting agent to prepare Granules, dried below 60°C, granulated, ready for use. Evodia rutaecarpa is extracted twice with 70% ethanol under reflux, the first time is 1 hour, the second time is 0.8 hours, the decoction is combined, filtered, recovered ethanol, concentrated to a thick paste, and reduced pressure at a vacuum d...

Embodiment 3

[0032] The parts by weight of each raw material in the formula of the traditional Chinese medicine for treating migraine described in the embodiment of the present invention are: Rhizoma Chuanxiong 563, Angelica dahurica 563, Evodia rutaecarpa 280 and Menthol 12.4.

[0033] Accurately weigh the weight of each raw material as follows: 563 grams of Rhizoma Chuanxiong, 563 grams of Angelica dahurica, 280 grams of Evodia rutaecarpa and 12.4 grams of menthol; 80% ethanol as a solvent, after soaking for 36 hours, percolate, collect the filtrate, recover ethanol from the filtrate, concentrate to a thick paste, add 1 times the amount of dextrin, mix well, use 95% ethanol as a wetting agent, and make Granules, dried below 60°C, granulated, ready for use. Evodia rutaecarpa was extracted twice with 70% ethanol under reflux, the first time was 3 hours, the second time was 2.5 hours, the decoction was combined, filtered, ethanol was recovered, concentrated to a thick paste, and the pressur...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine for treating migraine and a preparation method thereof. The formulation of the traditional Chinese medicine for treating the migraine comprises the following raw materials in parts by weight: 187-563 parts of Szechuan lovage rhizome, 187-563 parts of radix angelicae, 93-280 parts of fructus evodiae and 4.1-12.4 parts of menthol crystal. The preparation method for the traditional Chinese medicine for treating the migraine comprises the following steps: 1) weighing the raw materials according to the proportioning; 2) crushing, percolating and concentrating the Szechuan lovage rhizome and the radix angelicae to granulate, and then drying and finishing granule; 3) extracting the fructus evodiae, drying under reduced pressure to obtain a dry extract; 4) packing the menthol crystal and drying; and 5) mixing and crushing the fructus evodiae dry extract and the beta cyclodextrin clathrate compound of the menthol crystal, sieving to granulate, drying, finishing granule, and mixing evenly with the Szechuan lovage rhizome and radix angelicae granule and then encapsulating.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating migraine and a preparation method thereof. Background technique [0002] Migraine is a periodic attack of headache, often recurrent, seriously affecting the life and work of patients. There are approximately 240 million migraine sufferers in the world. According to the 1988 International Headache Society (IHS) diagnostic criteria, the prevalence rate in the United States is 17.6% for women and 6% for men. The annual incidence of migraine in my country in 1983 was 20.2 / 100,000, the prevalence rate was 523.9 / 100,000. According to WHO, severe migraine ranks among the top 20 most common medical diseases that incapacitate people. [0003] At present, the exact pathophysiological mechanism of migraine is still unclear in western medicine, although some western medicines such as serotonin receptor agonists, ergotamines, non-steroidal anti-in...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/754A61P25/06
Inventor 范吉平
Owner SHANGHAI KAIBAO PHARMA