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Compound orthophaladetyde phenyl ammonium chloride disinfectant and preparation method thereof

A technology of o-phthalaldehyde phenylammonium chloride and o-phthalaldehyde, applied in the direction of disinfectants, botany equipment and methods, biocides, etc., can solve the problem of easy oxidation damage, unstable properties, bacteria and spore killing In order to achieve good anti-oxidation effect, inhibit oxidation process and improve permeability

Active Publication Date: 2010-12-29
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, o-phthalaldehyde also has obvious disadvantages, mainly in that its killing effect on bacteria and spores is not ideal, and its properties are unstable and easily destroyed by oxidation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Add 3 grams of o-phthalaldehyde into 985 grams of water, stir and dissolve; add 5 grams of dipotassium hydrogen phosphate, 4 grams of potassium dihydrogen phosphate, 1 gram of sodium polyacrylate, 0.5 grams of sodium erythorbate, and 2 grams of ethylenediaminetetraacetic acid. 0.5 gram of sodium, stirred and dissolved; Added 1 gram of phenylammonium chloride, stirred and dissolved, to obtain the compound o-phthalaldehyde phenylammonium chloride disinfectant.

Embodiment 2

[0032] Add 5 grams of o-phthalaldehyde into 985.8 grams of water, stir and dissolve; add 2 grams of dipotassium hydrogen phosphate, 2 grams of potassium dihydrogen phosphate, 2 grams of sodium polyacrylate, 0.5 grams of sodium erythorbate, 0.5 grams of sodium ascorbate, and 0.2 gram of disodium diamine tetraacetate was stirred and dissolved; 2 grams of phenylammonium chloride was added, stirred and dissolved to obtain the compound o-phthalaldehyde phenylammonium chloride disinfectant.

Embodiment 3

[0034] Add 10 grams of o-phthalaldehyde to 971 grams of water, stir and dissolve; add 8 grams of dipotassium hydrogen phosphate, 6 grams of potassium dihydrogen phosphate, 3 grams of sodium polyacrylate, 0.5 grams of sodium ascorbate, and disodium edetate 1 gram, stirring and dissolving; Adding 0.5 gram of phenylammonium chloride, stirring and dissolving, obtains the described compound o-phthalaldehyde phenylammonium chloride disinfectant.

[0035] Above-mentioned each embodiment disinfectant soaks stainless steel sheet, carbon steel sheet, copper sheet, aluminum sheet continuously for 14 days, and all no corrosion phenomenon is seen.

[0036] Suspension quantitative bactericidal test, under the condition of 19-21 ℃, the killing rate of Staphylococcus aureus, Escherichia coli, and Candida albicans is 100% under the condition of 19-21 °C for 2 minutes; the killing rate of Bacillus subtilis var. The rate is 100%.

[0037] Accelerated stability test results show that when stored...

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PUM

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Abstract

The invention relates to a compound orthophaladetyde phenyl ammonium chloride disinfectant and a preparation method thereof. The compound orthophaladetyde phenyl ammonium chloride disinfectant comprises the following components by weight: 0.2-1 wt% of orthophaladetyde, 0.05-0.5 wt% of phenyl ammonium chloride, 0.1-1 wt% of dipotassium phosphate, 0.1-1 wt% of monopotassium phosphate, 0.1-0.3 wt% of sodium polyacrylate, 0.05-0.2 wt% of antioxidant, 0.01-0.1 wt% of disodium ethylene diamine tetraacetic acid and the balance of water. The preparation method of the compound orthophaladetyde phenyl ammonium chloride disinfectant comprises the following steps of: adding the orthophaladetyde into water according to the content and components, and stirring for dissolving; adding the dipotassium phosphate, the monopotassium phosphate, the sodium polyacrylate, the antioxidant and the disodium ethylene diamine tetraacetic acid in sequence, and stirring for dissolving; and adding the phenyl ammonium chloride, and stirring for dissolving to obtain the compound orthophaladetyde phenyl ammonium chloride disinfectant. The disinfectant is applicable to the high-level disinfection of thermolabile medical apparatus and instruments. The disinfectant has no pungent smell, safety, low toxicity, stable properties and convenient use.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a compound o-phthalaldehyde phenyl ammonium chloride disinfectant and a preparation method thereof. Background technique [0002] Phthalaldehyde is a new type of aldehyde chemical disinfectant, which has the characteristics of low corrosion, non-volatile, low irritation, and can be used directly without activation. It was used for endoscope disinfection in foreign countries in 1994. It was found to have a good disinfection effect. In 1999, o-phthalaldehyde was certified by the FDA of the United States. As a high-level disinfectant, it can be used to repeatedly treat heat-sensitive medical equipment, and it can quickly and high-level disinfect at a room temperature of 20°C. However, o-phthalaldehyde also has obvious disadvantages, mainly in that its killing effect on bacteria and spores is not ideal, and its properties are unstable and easily destroyed by oxidation. [0003] Phenyl ammonium chl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/26A01N35/04A01N33/12A01N37/44A01N37/06A01P1/00
Inventor 张万国张忠敏葛莉娟
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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