Magnetic stirring bioreactor and magnetic stirring system

Abstract

The invention discloses a magnetic stirring bioreactor and a magnetic stirring system, which comprises a magnetic steel driving disc, a magnetic steel driven disc, a fixed shaft, a stirring shaft, a stirring paddle and a positioning piece, wherein the magnetic steel driving disc is arranged outside a reaction cavity and rotates under the action of a driving force; the magnetic steel driven disc is arranged in a reaction cavity and at the bottom of the reaction cavity; the stirring shaft is arranged in the reaction cavity and fixedly connected with the magnetic steel driven disc and is sleevedon the fixed shaft together with the magnetic steel driven disc; the stirring paddle is arranged on the stirring shaft; and the positioning piece is arranged on the stirring shaft and pressed againstthe fixed shaft for regulating the distance between the magnetic steel driven disc and the magnetic steel driving disc. In the invention, a static seal magnetic force-driven stirring shaft without dynamic shaft seal feeding is used to reduce the chance for microbiological contamination and solve the leakage problem of the medium in the reactor. In addition, with a single-end supporting structure,the magnetic stirring bioreactor can be installed and cleaned more conveniently, and the structure of the reactor is more reasonable.

Description

technical field [0001] The invention relates to a biotechnology process, in particular to a magnetic stirring bioreactor and a magnetic stirring system thereof. Background technique [0002] In the field of biotechnology, the existing small-scale and pilot-scale reactors use various stirring systems, such as gas stirring, mechanical stirring systems, etc. Among them, the mechanical stirring system has a mechanical stirring system in which the motor is directly connected to the stirring shaft and the magnetic drive is separated from the shaft. The motor is directly connected to the stirring shaft, which involves the dynamic sealing of the shaft and the reactor. Due to the temperature resistance and pressure resistance of the sealing material, such a reactor has the possibility of leakage and contamination, especially in microbial cultivation. In the mechanical stirring system with magnetic drive, the seal between the shaft and the reactor adopts a static seal, which reduces ...

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