Medicine for treating coronary heart disease and preparation method thereof

A technology for coronary heart disease and a drug, applied in the field of preparation of the drug, can solve the problems of unclear mechanism of action, unclear curative effect, complex composition, etc., and achieve the effects of improving quality of life, fewer drug components, and dilating blood vessels

Inactive Publication Date: 2011-05-11
安冬青
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few studies from the perspective of improving myocardial oxygen consumption and restoring endothelial cell function
At the same time, most of the traditional Chinese medicine compositions in the prior art have many components, complex components, unknown specific mechanism of action, and unclear curative effect.

Method used

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  • Medicine for treating coronary heart disease and preparation method thereof
  • Medicine for treating coronary heart disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] (1) Take the raw materials according to the following proportioning ratio: Rhodiola rosea, Salvia miltiorrhiza, Xintahua, and Dalbergia in parts by weight are 3:4:3:1;

[0089] (2) Rhodiola rosea and Salvia miltiorrhiza were crushed into 10-mesh coarse powder, impregnated with 10 times the amount of 65% and 90% ethanol respectively, and the percolation was completed slowly, and the ethanol was recovered from the filtrate and concentrated to a thick paste with a relative density of 1.30 at 60°C spare;

[0090] (3) Add 10 times the amount of water for Jiangxiang and Xintahua to soak overnight, steam distill for 2 hours, collect volatile oil, and store the volatile oil separately; filter the aqueous solution after distillation, and store separately for later use;

[0091] (4) Add 10 times the amount of water to decoct the dregs of rhodiola and salvia miltiorrhiza for 1 hour, filter, combine the dregs with the distilled dregs of xiangxiang and xintahua, and then add 10 time...

Embodiment 2

[0094] (1) Take the raw materials according to the following proportioning ratio: Rhodiola rosea, Salvia miltiorrhiza, Xintahua, and Dalbergia in parts by weight are 6:5:4:2;

[0095] (2) Rhodiola rosea and Salvia miltiorrhiza were crushed into 10-mesh coarse powder, impregnated with 10 times the amount of 70% and 90% ethanol respectively, and the percolation was completed slowly, and the ethanol was recovered from the filtrate and concentrated to a thick paste with a relative density of 1.30 at 60°C spare;

[0096] (3) Add 10 times the amount of water for Jiangxiang and Xintahua to soak overnight, steam distill for 2 hours, collect volatile oil, and store the volatile oil separately; filter the aqueous solution after distillation, and store separately for later use;

[0097] (4) Add 10 times the amount of water to decoct the dregs of rhodiola and salvia miltiorrhiza for 1 hour, filter, combine the dregs with the distilled dregs of xiangxiang and xintahua, and then add 10 time...

Embodiment 3

[0100] (1) The raw materials are weighed according to the following proportions: Rhodiola rosea, Salvia miltiorrhiza, Xintahua, and Dalbergia in parts by weight ratio of 5:5:3:2;

[0101] (2) Take Rhodiola rosea and add 9 times the amount of ethanol to reflux and extract three times, reclaim the ethanol, concentrate to a thick paste, and set aside;

[0102] (3) take Danjiu 12 times the amount of ethanol and reflux extraction twice, reclaim ethanol, concentrate to a thick paste, and set aside;

[0103] (4) Take Jiangxiang, Xintahua, Rhodiola rosea and Salvia miltiorrhiza after alcohol extraction, add 9 times the amount of water to extract twice, collect the volatile oil at the same time for the first time, combine the medicinal liquid for the second time, filter, and centrifuge the filtrate , filtered, the filtrate was concentrated to a thick paste, combined with the above two thick pastes, dried, pulverized into fine powder, added microcrystalline cellulose, and made into gran...

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Abstract

The invention relates to a medicine for treating coronary heart disease and a preparation method thereof. The medicine is prepared by the following raw materials in percentage by weight: 3-6 of rhodiola root, 3-6 of salvia miltiorrhiza, 2-4 of Ziziphora bungeana and 1-3 of lignum dalbergiae odoriferae, and the ingredients of the raw materials are extracted and then used together with other auxiliary materials to be prepared into granules or capsules. The medicine for treating coronary heart disease has less medicinal ingredients, definite curative effect, and the effects of improving symptom of myocardial ischemia, improving the ECG (electrocardiogram), preventing platelet aggregation, dilating the blood vessel and improving the life quality of patients with coronary heart disease and angina pectoris.

Description

technical field [0001] The invention relates to a medicine for treating coronary heart disease, specifically a Chinese patent medicine prepared from Chinese herbal medicine, and also relates to a preparation method of the medicine. Background technique [0002] Coronary heart disease is a frequently-occurring common disease, and it is on the rise in recent years. At present, there are three methods for the treatment of coronary heart disease: drug therapy, interventional therapy and surgery. The main disadvantage of interventional or surgical bypass therapy is intravascular restenosis. Therefore, regardless of choosing intervention or surgical bypass, drug treatment is a necessary supplement, and some drugs even need to be taken for life. [0003] Although western medicine has made great progress in the diagnosis and treatment of coronary heart disease, there are still many insurmountable defects, and these are exactly the advantages of traditional Chinese medicine. Tradi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61P9/10
Inventor 安冬青
Owner 安冬青
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