Method for improving anticancer activity of Codonopsis lanceolata Benth.et Hook.F

Abstract

The invention relates to a method for improving the anticancer activity for Codonopsis lanceolata Benth.et Hook.F, which comprises: slicing or homogenizing fresh Codonopsis lanceolata Benth.et Hook.F, or crushing dry Codonopsis lanceolata Benth.et Hook.F, or powdering the dry Codonopsis Lanceolata Benth.et Hook.F; soaking in water; sterilizing under a high pressure; adding 0.5 to 5.0 percent of active yeast and 1 to 8 percent of glucose under a sterile condition when the temperature lowers to 30 DEG C; fermenting at 20 to 37 DEG C for 1 to 10 days, and adding a polar solvent after fermentation to extract for 5 to 24 hours at 0 to 100 DEG C; and filtering, recovering solvent and concentrating under reduced pressure or drying by freezing. The method can improve the inhibition effect of Codonopsis lanceolata Benth.et Hook.F on the growth of tumors.

Description

A method for improving the anticancer activity of Codonopsis verticillum technical field The invention relates to a method for increasing the anticancer active ingredient in Codonopsis verticillum, in particular to a method for increasing the content of the anticancer active ingredient in Codonopsis verticillum by using yeast fermentation technology. Background technique Codonopsis Lanceolata Benth. et Hook. F., also known as goat's milk, four-leaf ginseng, mountain carrot, mountain conch and white python meat, is the root of Codonopsis Lanceolata Benth. et Hook. F., mostly distributed in Northeast China, South China, In Southwest China, North Korea, Japan, Russia and other countries, it is often eaten as a wild vegetable among the people. Traditionally, its root is used as medicine, sweet in taste and flat in nature. It is mainly used for symptoms such as physical weakness after illness, lack of milk, lung yin deficiency, carbuncle, breast carbuncle, sore and swelling. ...

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Problems solved by technology

However, after soaking Codonopsis vermicelli in a certain concentration of ethanol aqueous solution for 24 hours, the obtained extract had no obvious inhibitory effect on tumor growth in mice

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