Decolorized ganoderma lucidum polysaccharide extract and method for preparing hand cream by using same

A technology of Ganoderma lucidum polysaccharide and extract, which is applied to cosmetic preparations, skin care preparations, pharmaceutical formulations, etc., can solve the problems of long decolorization time, large loss rate of polysaccharides, rough texture, etc., and achieves obvious moisturizing effect and pure color. White, fine-textured effect

Active Publication Date: 2012-09-05
GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the Ganoderma lucidum polysaccharides obtained by water extraction and alcohol precipitation generally have the reddish brown color of Ganoderma lucidum itself. When directly added to the cream, the product will have a darker reddish brown color, poor appearance color, and rough texture.
At present, the decolorization methods of polysaccharide extracts generally adopt activated carbon adsorption method, hydrogen peroxide oxidation method and macroporous resin adsorption method. Among them, the decolorization time of activated carbon method is long and the loss rate of polysaccharide is large. Hydrogen peroxide oxidation method will cause damage to the polysaccharide structure and affect its biological activity.
Macroporous resin has a strong ability to adsorb pigments, its decolorization rate can reach more than 85%, and the polysaccharide retention rate can reach more than 85%, but the process is more complicated and the cost is higher

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] After taking 10g of Ganoderma lucidum fruiting body slices, add 100mL of distilled water, reflux the hot water at 75°C to extract once, add ethanol to the extract to make the final concentration of ethanol 60%, let it settle at 4°C for 10h, filter it with suction, and dry the precipitate at 40°C dry and pulverize to obtain Ganoderma lucidum polysaccharide powder.

[0019] Weigh 1g of Ganoderma lucidum polysaccharide powder, dissolve it in 500mL of water and mix to make a solution, add 5.01g of activated carbon, adjust the pH to 2.5, ultrasonically mix for 20s, let stand at 20°C for 20min, 4000r·min -1 Centrifuge for 10 min, and take the supernatant to obtain a colorless and transparent Ganoderma lucidum polysaccharide extract. The content of Ganoderma lucidum polysaccharide was determined by phenol sulfuric acid method, and the decolorization rate of Ganoderma lucidum polysaccharide was determined by measuring the OD of the sample before and after decolorization. 490nm...

Embodiment 2

[0021] After taking 10g of Ganoderma lucidum fruiting body slices, add 500mL of distilled water, reflux the hot water at 99°C to extract three times, add ethanol to the extract to make the final concentration of ethanol 90%, let stand at 25°C for 24h, filter with suction, and dry the precipitate at 60°C dry and pulverize to obtain Ganoderma lucidum polysaccharide powder.

[0022] Weigh 2.5g Ganoderma lucidum polysaccharide powder, dissolve it in 500mL water and mix to make a solution, add 15.075g activated carbon, adjust the pH to 4.5, ultrasonically mix for 60s, let stand at 40°C for 100min, 10000r·min -1 After centrifuging for 30 min, the supernatant was taken to obtain a colorless and transparent Ganoderma lucidum polysaccharide extract, with a decolorization rate of 99.5% and a polysaccharide retention rate of 66.6%.

Embodiment 3

[0024] 100 g of the decolorized ganoderma polysaccharide extract of Example 1, 25 g of propylene glycol, 0.1 g of triethanolamine and 0.05 g of propylparaben are made into the water phase, and then 4 g of mineral oil, 1 g of lanolin and 2 g of cetyl alcohol are made into the oil phase . Heat the oil phase and water phase respectively until dissolved, keep the temperature at 50°C, and keep the rotation speed at 320r·min -1 , slowly add the oil phase into the water phase, emulsify for 5 minutes, let stand and cool to room temperature to obtain hand cream.

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Abstract

The invention relates to decolorized ganoderma lucidum polysaccharide extract and a method for preparing hand cream by using the same. The decolorized ganoderma lucidum polysaccharide extract is characterized by being prepared by the following steps: performing refluxing extraction in hot water on ganoderma lucidum fruiting body, precipitating in ethanol, performing suction filtration, drying theprecipitate, grinding the precipitate to obtain ganoderma lucidum powder, adding deionized water, uniformly mixing to prepare solution, adding active carbon according to a principle that the mass of the active carbon is 1 to 3 percent based on the total mass of the solution, uniformly mixing by ultrasonic waves, centrifuging at a rotation speed of 4,000 to 10,000r.min<-1>, and collecting supernate to obtain the colorless transparent ganoderma lucidum extract; preparing a water phase by using the extract, propylene glycol, triethanolamine and propylparaben, preparing an oil phase by using mineral oil, lanolin and cetanol, heating the oil phase and water phase respectively till the solutes dissolve, adding the oil phase into the water phase, emulsifying, standing and cooling to prepare the hand cream. When the method is used, the decolorizing rate of the ganoderma lucidum reaches 99.6 percent, the retention rate of the ganoderma lucidum reaches 66.7 percent, and the hand cream prepared by the ganoderma lucidum is pure white, fine and lubricant, has obvious moisturizing effect and gives off natural fragrance of ftillgi.

Description

technical field [0001] The invention relates to a ganoderma polysaccharide extract, in particular to a ganoderma polysaccharide extract obtained by using active carbon and ultrasonic decolorization; in addition, it also relates to a method for preparing hand cream with the ganoderma polysaccharide extract. Background technique [0002] In modern society, people are not only exposed to various electromagnetic radiation environments for a long time, but also often have to be exposed to various chemical lotions (detergents, soaps, washing powder, etc.), resulting in skin dehydration or a decline in antioxidant capacity. Inelastic, dry, rough. Most of the existing skin care and hand care products are mainly chemical ingredients containing heavy metals. Although they can moisturize and whiten the skin, long-term use will cause skin thinning, and accumulation will lead to more serious skin problems. Natural, effective Skin care and hand care products that nourish the skin and inc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/00A61K8/92A61K8/73A61Q19/00
Inventor 宋斌曾宏彬李泰辉
Owner GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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