Processing method for industrially producing rabbit brain powder

Abstract

The invention discloses a processing method for industrially producing rabbit brain powder. The method is characterized by comprising the following processes of: taking fresh rabbit brain, soaking the rabbit brain into cold acetone, fishing out the rabbit brain, removing blood vessels and meninges, adding the treated rabbit brain into the cold acetone, mixing the rabbit brain and the cold acetoneuniformly by using a homogenizer, performing centrifugation to remove the acetone solvent, and drying the rabbit brain powder. The method has the advantages that: because the traditional mortar for grinding is substituted by using the homogenizer, the activity of tissue factors in the rabbit brain is kept; the taken fresh rabbit brain is directly soaked into the cold acetone to substitute the traditional brine washing, so that the velocity of removing the blood vessels and the meninges in the rabbit brain is improved and the activity of the tissue factors is improved; the velocity of gas jet impact drying for rabbit brain powder protection with gas is improved by 2 to 3 times compared with the velocity of the traditional vacuum drying, and the rabbit brain powder is thinner, higher in activity and purer in color; and the whole method is high in production efficiency, and can realize industrialized large-scale production.

Description

technical field [0001] The invention relates to a processing method of rabbit brain powder, in particular to a processing method for industrial production of rabbit brain powder. Background technique [0002] Tissue factor is a membrane-bound lipid-dependent glycoprotein, which can form a complex with coagulation factor VII and significantly improve the activation ability of coagulation factor VII to factors X and IX. Tissue factor plays a hemostatic effect by activating the coagulation cascade reaction. Rabbit brain powder extracted with acetone is rich in tissue factor, so rabbit brain powder is widely used in medical clinical tests. [0003] The current preparation method of rabbit brain powder is as follows: take fresh rabbit brain, peel off the meninges and blood vessels, wash it with normal saline, cut it into pieces, then add an appropriate amount of acetone to grind, let the brain powder settle, and pour off the upper layer of acetone solution, Repeat this several...

AI Technical Summary

Problems solved by technology

[0003] The current preparation method of rabbit brain powder is as follows: take fresh rabbit brain, peel off the meninges and blood vessels, wash it with normal saline, cut it into pieces, then add an appropriate amount of acetone to grind, let the brain powder settle, and pour off the upper layer of acetone solution, Repeat this several times until the brain powder is off-white, then place the brain powder in a vacuum drying oven to dry, and completely evaporate the acetone solvent to obtain rabbit brain powder; In the process, it is easy to lose the activity of tissue factor in the rabbit brain powder, and the yield is extremely low