Carbamazepine immunogen, anti-carbamazepine specific antibody, detection reagent and detection kit
Patent Information
- Authority / Receiving Office
- CN ยท China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HAINAN JINYU MEDICAL TESTING CENT CO LTD
- Publication Date
- 2011-09-14
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Abstract
Description
technical field
[0001] The invention relates to a carbamazepine immunogen, an anti-carbamazepine specific antibody, a detection reagent and a detection kit. Background technique
[0002] Carbamazepine (5 H -dibenzo[ b , f ]azepine-5-carboxamide, 5H-dibenzo[b,f]azepine-5-carboxamide), its structural formula is shown in formula (II).
[0003]
[0004] Carbamazepine is a class of antiepileptic and mood stabilizing drugs, mainly used in the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. Carbamazepine has many side effects, including: anaphylaxis that may be life-threatening; toxicity to the trigeminal nerve that may cause severe damage to the skin and internal organs. It is therefore very important to monitor the patient's blood drug levels during treatment.
[0005] The immunoassay method established by using the specific antibody against carbamazepine has been applied to the tracking and monitoring of carbamazepine in the patient's blood. Existing a...