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Chinese medicinal composition for treating depression

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, to achieve the effect of broad market prospects

Inactive Publication Date: 2011-12-07
TIANJIN TAIYANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Could overcome shortcomings of existing antidepressants

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0038] Using methods known to those skilled in the art, 10 kg of ginkgo leaves were extracted with 60 liters of 80% ethanol aqueous solution at 80°C under reflux, the ethanol was recovered, filtered, ME-1 column chromatography (provided by Tianjin Ou Rui Biotechnology Co., Ltd.), Concentrate and dry to obtain Ginkgo biloba extract (26% ginkgo flavonoids, 8% ginkgolides, 2ppm ginkgolic acid); 20 kg of psoralen is extracted with 120 liters of 70% ethanol aqueous solution at 80°C under reflux, ethanol is recovered, filtered, ME- 1 Column chromatography (provided by Tianjin Orui Biological Technology Co., Ltd.), concentrated and dried to obtain psoralen extract (bakuchiol 25%). Mixing ginkgo biloba extract and psoraleae extract to obtain prescription 1 of the present invention.

specific Embodiment 2

[0039]Using methods known to those skilled in the art, 50 kilograms of ginkgo leaves were extracted with 300 liters of 80% ethanol aqueous solution at 80°C under reflux, ethanol was recovered, filtered, and ME-1 column chromatography (provided by Tianjin Orui Biotechnology Co., Ltd.) , Concentrated and dried Ginkgo biloba extract; Ginkgo biloba extract was dissolved in 100 liters of water, passed through MG-1 (provided by Tianjin Orui Biotechnology Co., Ltd.) adsorption resin column, connected to the effluent, concentrated and crystallized Ginkgolide extracted (total ginkgo lactones 75%); 100 kilograms of psoraleae were extracted with 600 liters of 70% ethanol aqueous solution at 80 ° C under reflux, reclaimed ethanol, filtered, and ME-1 column chromatography (provided by Tianjin Ou Rui Biotechnology Co., Ltd.) , concentrated, dried psoralen extract. Bakuchiol extract is dissolved in 200 liters of 80% ethanol aqueous solution, by OU-1 (Tianjin Ou Rui Biological Technology Co.,...

Embodiment 3

[0041] By the 0.5 kilogram of ginkgolide content obtained in embodiment 2 is the extract that is 70%, the extract that 0.5 kilogram of bakuchiol content is 55% is mixed, adopts conventional technology to make medicine dropping pill.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating depression, which consists of 2-10 ginkgo biloba extracts and 2-20 psoraleae extracts in parts by weight. Ginkgo biloba extract is water or ethanol extract of ginkgo biloba, and psoraleae extract is water or ethanol extract. The Ginkgo biloba extract is a standard Ginkgo biloba extract or an extract of total ginkgo lactones. The said psoralen extract is psoralen extract or bakuchiol extract. The composition is aimed at each link of the onset of depression, exerts pharmacological effects on multiple targets, avoids the toxicity and side effects of chemical drugs, and is a therapeutic and preventive drug for depression with broad market prospects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition whose main function is to treat depression. technical background [0002] Mental diseases and or neurological diseases are important diseases that seriously threaten human health. Depression is a kind of mental or neurological disease, which is mainly manifested as low mood, pessimism, and negativity, and can lead to suicide in severe cases. According to statistics, about 25% of women in the general population have experienced depression in their lifetime, and about 10% of men have experienced depression ("Modern Psychology" by Zhang Chunxing). At present, the incidence of depression in the world is about 11%, and there are about 340 million depressed patients in the world, and this number is still on the rise. The World Health Organization predicts that depression will become the second major clinical chronic disease after...

Claims

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Application Information

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IPC IPC(8): A61K36/487A61P25/24
Inventor 欧来良王为超
Owner TIANJIN TAIYANG PHARMA
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