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Compound pumpkin vine ointment and preparation method thereof

A pumpkin vine and ointment technology, which is applied in ointment delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as easy fermentation, unsuitable storage, and the cure rate of diseases does not play a decisive role, achieving quick results , easy to promote and use, and low-cost effects

Inactive Publication Date: 2013-03-20
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, practice has proved that the ointment can relieve symptoms quickly for cases with severe redness, swelling, heat and pain, but it does not play a decisive role in the cure rate of the disease.
Some patients have skin contact reactions, and the drug is easy to ferment, so it is not suitable for storage. The composition and production method of the drug affect the penetration ability of the drug, which relatively reduces the bioavailability of the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The compound pumpkin vine ointment involved in the present embodiment, calculated in 1000g, is composed of: pumpkin vine (charcoal) 61.73g, Glauber's salt 49.38g, neem fruit (charcoal) 12.35g, phenol 20.58g, flour 205.76g, The balance is water and caramel.

[0022] The preparation method of this embodiment:

[0023] Take calcined pumpkin vine (charcoal) and neem seeds (charcoal), take Glauber's salt and add 83ml of water to heat to dissolve, filter, collect the filtrate and add 61.73g of pumpkin vine (charcoal) that has been crushed into fine powder and sieved , neem seeds (charcoal) 12.35g and mix thoroughly, then add maltose and mix thoroughly, then add 205.76g flour, stir until uniform while adding, finally add 20.58g phenol, stir well, make 1000g, and get it.

[0024] Applying this embodiment to clinical practice, respectively select two groups of ten cases of sore cases with severe redness, swelling, heat and pain:

[0025] group Treatment time (days) ...

Embodiment 2

[0026] Embodiment 2: This embodiment is aimed at patients with sores and ulcers with "swelling" symptoms.

[0027] The difference between this embodiment and Example 1 is the difference in the composition of raw materials. The compound pumpkin vine ointment involved in this embodiment is calculated in 1000g. Neem (charcoal) 2.35g, phenol 30.58, flour 255.76, and the balance is water and maltose.

[0028] This embodiment is used clinically, and three groups of ten cases of sore cases with more serious "swollen" symptoms are selected respectively:

[0029] group Treatment time (days) cure markedly effective efficient invalid Total effective rate% black ointment group 14 6 1 1 2 80% Example 1 14 8 1 0 1 90% Example 2 14 8 2 0 0 100%

Embodiment 3

[0030] Embodiment 3: This embodiment is aimed at sore patients with "fever" symptoms.

[0031] The difference between this example and Example 1 is the difference in the composition of the raw materials. The compound pumpkin vine ointment involved in the present embodiment is calculated in 1000g, and the composition of the raw materials is: pumpkin vine (charcoal) 71.73, Glauber’s salt 44.38, neem seeds (Charcoal) 7.35, phenol 10.58, flour 155.76, and the balance is water and caramel.

[0032] This embodiment is used clinically, and three groups of ten cases of sores with severe "fever" symptoms are selected respectively:

[0033] group Treatment time (days) cure markedly effective efficient invalid Total effective rate% black ointment group 14 6 1 1 2 80% Example 1 14 8 1 0 1 90% Example 3 14 9 1 0 0 100%

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Abstract

The invention particularly relates to a compound pumpkin vine ointment and a preparation method thereof. Every 1000 parts by weight of ointment comprises the following active pharmaceutical ingredients in parts by weight: 51.73-71.73 parts of pumpkin vine (carbonized), 39.38-49.38 parts of mirabilite, 2.35-22.35 parts of Chinaberry seed (carbonized), 10.58-30.58 parts of phenol, 155.76-255.76 parts of flour, and the balance of water and caramel. The preparation method comprises the following steps: adding mirabilite into a certain amount of water, heating to dissolve the mirabilite, filtering, and collecting the filtrate; adding pumpkin vine (carbonized) and Chinaberry seed (carbonized) which are pulverized into fine powder and screened, evenly mixing, adding a right amount of caramel, evenly mixing, and adding flour while evenly stirring; and finally, adding phenol, and evenly mixing to obtain the compound pumpkin vine ointment. The compound pumpkin vine ointment has comprehensive and unique effects on diminishing inflammations, removing toxicity, promoting the subsidence of swelling, alleviating pain, evacuating pus, promoting blood circulation and dredging collaterals for ulcerand furuncle, and can be effectively used in acute and chronic stages of ulcer as well as early, medium and later stages of ulcer. The compound pumpkin vine ointment can quickly take effect, and is not irritating to skin.

Description

technical field [0001] The invention relates to an external application ointment of a pharmaceutical composition and a preparation method thereof, in particular to a compound pumpkin vine ointment and a preparation method thereof. Background technique [0002] The "black ointment" product used to treat osteomyelitis in the prior art consists of 150 grams of sun-dried calcined charcoal of pumpkin vine, 30 grams of calcined charcoal preservation of neem, 120 grams of Glauber's salt, 500 grams of ground root powder, and 1000 grams of maltose , 150 grams of glycerin. Grind the above medicines (except maltose and glycerin) into fine powder, heat them in a copper pot, add maltose and glycerin to boil. Function anti-inflammatory, pain relief, detumescence, detoxification. According to experimental research, the anti-infection mechanism of the "black ointment" does not directly inhibit bacteria, nor directly weaken or eliminate the virulence of bacteria, it may be through promotin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/58A61K9/06A61P17/02A61P19/08A61K33/04A61K31/7016A61K31/05
Inventor 李萍虞坚尔陈诗吟吕祥张思嘉王臬吴林辉周园明蔡烽周芳杨新伟徐光耀
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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