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A traditional Chinese medicine composition for treating systemic lupus erythematosus

A technology of lupus erythematosus and composition, which is applied in the field of traditional Chinese medicine composition for treating systemic lupus erythematosus, can solve problems such as not being able to meet the actual needs of systemic lupus erythematosus, and achieve the effect of abundant raw materials, scientific composition, and easy production

Inactive Publication Date: 2011-12-21
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to various reasons, it cannot meet the actual needs for the treatment of systemic lupus erythematosus, so its innovation is imperative

Method used

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  • A traditional Chinese medicine composition for treating systemic lupus erythematosus
  • A traditional Chinese medicine composition for treating systemic lupus erythematosus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] In practice, the present invention is made from the following components by weight: 15 parts of lily, 15 parts of raw land, 15 parts of cassia twig, 15 parts of peach kernel, 15 parts of anemarrhena, 40 parts of angelica, 25 parts of scrophulariaceae, white peony 25 parts, 25 parts of Cortex Moutan, 25 parts of Atractylodes Rhizoma Atractylodes Rhizome, 25 parts of Cornus officinalis and 15 parts of Agrimony, wherein Lily, Anemarrhena, Radix Paeoniae Alba, Moutan Cortex and Agrimony are mixed together, and the mass concentration of adding 8 times its weight is 75 % of ethanol, heated and refluxed for 4 hours, filtered, and the filtrate was decompressed to recover the ethanol to obtain the medicinal liquid, which was concentrated to 1 / 2 of the original volume to make liquid A; , Bai Shu and dogwood mixed together, add 8 times the weight of water, fry twice, 1.5 hours each time, combine the decoction, filter and filter fluid decompression to 1 / 2 of the original volume,...

Embodiment 2

[0013] Preparation of granules

[0014] The preparation of granules is specifically carried out according to the following steps:

[0015] (1) Weigh each raw material according to the following parts by weight: 150g lily, 150g raw land, 150g cassia twig, 150g peach kernel, 150g anemarrhena, 400g angelica, 250g scrophulariae, 250g white peony root, 250g moutan cortex, 250g atractylodes macrocephala, 250g dogwood , Agrimony 150g;

[0016] (2) Add the weighed Lily, Anemarrhena, Radix Paeoniae Alba, Cortex Moutan, and Agrimony with 75% ethanol at 8 times the weight, heat and reflux for extraction for 4 hours, filter, and recover ethanol from the filtrate under reduced pressure, and concentrate to 1 / 3 , make A;

[0017] (3) Decoct Shengdi, Guizhi, Taoren, Angelica, Scrophulariae, Atractylodes macrocephala, and Cornus officinalis with 8 times the weight of water twice, each time for 1.5 hours, combine the decoctions, filter, and concentrate the filtrate under reduced pressure ...

Embodiment 3

[0020] Tablet preparation

[0021] The preparation of tablet specifically carries out according to the following steps:

[0022] (1) Weigh each raw material according to the following parts by weight: 150g lily, 150g raw land, 150g cassia twig, 150g peach kernel, 150g anemarrhena, 400g angelica, 250g scrophulariae, 250g white peony root, 250g moutan cortex, 250g atractylodes macrocephala, 250g dogwood , Agrimony 150g;

[0023] (2) Mix the weighed Lily, Anemarrhena, Radix Paeoniae Alba, Cortex Moutan, and Agrimony together, add 8 times the weight of 75% ethanol, heat and reflux for extraction for 4 hours, filter, and recover the ethanol from the filtrate under reduced pressure, and concentrate to 1 / 3, made into liquid A;

[0024] (3) Mix the weighed raw land, cinnamon sticks, peach kernels, angelica, scrophulariae, Atractylodes macrocephala, and dogwood together, add 8 times the weight of water to decoct twice, each time for 1.5 hours, combine the decoctions, filter, an...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating systemic lupus erythematosus, which can effectively solve the problem in application of medicines for treating systemic lupus erythematosus. The traditional Chinese medicine composition for treating systemic lupus erythematosus is prepared from the following components in parts by weight: 10-30 parts of lily root, 10-30 parts of radix rehmanniae, 10-30 parts of cassia twig, 10-30 parts of peach kernel, 10-30 parts of rhizoma anemarrhenae, 20-60 parts of angelica, 10-40 parts of figwort, 10-40 parts of radix paeoniae alba, 10-40 parts of moutan bark, 10-40 parts of rhizoma atractylodis macrocephalae, 10-40 parts of cornel and 10-30 parts of agrimony. The preparation method of the traditional Chinese medicine composition for treating systemic lupus erythematosus comprises the following steps: mixing lily root, rhizoma anemarrhenae, radix paeoniae alba, moutan bark and agrimony; adding alcohol, extracting byheating under reflux, filtering, recycling the alcohol under reduced pressure to obtain liquor, and concentrating the liquor to obtain a solution A; mixing radix rehmanniae, cassia twig, peach kernel, angelica, figwort, rhizoma atractylodis macrocephalae and cornel, adding water, decocting twice, merging the decoction solutions, filtering, concentrating to obtain a solution B; and mixing the solution A and the solution B, concentrating into clear paste, and adding auxiliary materials to obtain the traditional Chinese medicine composition preparation. The invention has the advantages of abundant raw materials, scientific formula, low cost and favorable curative effect, is easy to produce, and is a creation in traditional Chinese medicines.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating systemic lupus erythematosus. Background technique [0002] Systemic lupus erythematosus (SLE) is a common clinical autoimmune disease with multi-system damage that seriously threatens human health and life. It has a high mortality and disability rate and often occurs in 12- 40-year-old young and middle-aged female. According to statistics, the incidence rate in my country is about 70 / 100,000, and the number of patients in the country exceeds 1 million. [0003] For the treatment of SLE, there is no particularly effective drug in clinical practice. Western medicine mostly uses cytotoxic immunosuppressants such as glucocorticoids and cyclophosphamide to treat the disease, which has advantages in controlling lupus activity, but there are problems such as many adverse reactions and high recurrence rate after drug withdrawal. At prese...

Claims

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Application Information

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IPC IPC(8): A61K36/8967A61P37/02
Inventor 王培育车彦忠王培智高希言邵素菊张淑君华金双任珊何琦富野
Owner HENAN UNIV OF CHINESE MEDICINE
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