Buzhongyiqi granules and preparation method thereof

A technology of Buzhong Yiqi and granules, which is applied in the field of Buzhong Yiqi granules and its preparation, which can solve the problems of granule solubility, bad taste and smell of the solution, and affect patients' medication compliance, so as to achieve good taste and smell , The appearance of the solution is good, the effect of solubility is good

Active Publication Date: 2011-12-28
BEIJING HANDIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, it has been found in many years of production practice that Buzhong Yiqi Granules are only granulated with dextrin as an auxiliary material, and the solubility, appearance of the solution, taste and smell of the prepared granules are not good, which affects the medication compliance of patients to a certain extent sex

Method used

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  • Buzhongyiqi granules and preparation method thereof
  • Buzhongyiqi granules and preparation method thereof
  • Buzhongyiqi granules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1) Mix raw material medicines 180g of roasted Astragalus, 50g of Codonopsis, 90g of roasted licorice, 50g of Angelica, 50g of fried Baizhu, 50g of cohosh, 50g of Bupleurum, 50g of tangerine peel, 15g of ginger, and 35g of jujube, each time adding 5kg of water for decoction Cook for two times: the first decocted for 90 minutes to extract the decoction; the second decocted for 40 minutes to extract the decoction; combine the decoction, let stand, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.0 , The temperature is 80°C when measuring the relative density, and let cool to 20°C to obtain concentrated filtrate I;

[0024] 2) Add 95% ethanol aqueous solution of equal mass to the concentrated filtrate I, stir evenly, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.0. The temperature when measuring the relative density is 70°C to obtain concentrated filtrate II;

[0025] 3) Spray...

Embodiment 2

[0028] 1) Mix the raw material medicines of 220g of roasted Astragalus, 64g of Codonopsis, 110g of roasted licorice, 65g of Angelica, 65g of fried Baizhu, 65g of cohosh, 65g of Bupleurum, 65g of dried tangerine peel, 25g of ginger, and 45g of jujube. Add 7.9kg of water each time Decoction, decocted twice: the first decocted for 150 minutes to extract the decoction; the second decocted for 80 minutes to extract the decoction; combine the decoction, stand, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.3. When measuring the relative density, the temperature is 80°C, and let it cool to 30°C to obtain concentrated filtrate I;

[0029] 2) Add 95% ethanol aqueous solution of equal mass to the concentrated filtrate I, stir evenly, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.0. The temperature when measuring the relative density is 70°C to obtain concentrated filtrate II;

[0030] 3)...

Embodiment 3

[0033] 1) Mix the raw material medicines roasted astragalus 200g, codonopsis 60g, roasted licorice 100g, angelica 60g, fried atractylodes 60g, cohosh 60g, bleu 60g, tangerine peel 60g, ginger 20g, jujube 40g, and add 6.5kg of water each time Decoction, decocted twice: the first decocted for 120 minutes to extract the decoction; the second decocted for 60 minutes to extract the decoction; combine the decoction, stand, filter, and concentrate the filtrate under reduced pressure to a relative density of 11. When measuring the relative density, the temperature is 80°C, and let it cool to 25°C to obtain concentrated filtrate I;

[0034] 2) Add 95% ethanol aqueous solution of equal mass to the concentrated filtrate I, stir evenly, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.0. The temperature when measuring the relative density is 70°C to obtain concentrated filtrate II;

[0035] 3) Spray drying the concentrated filtrate...

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Abstract

A spleen-invigorating the qi-replenishing particle and a preparation method thereof of the invention relate to a composition which is mainly from plants and a preparation method thereof. The purpose is to provide a spleen-invigorating the qi-replenishing particle with good solubility, good solution appearance, and good taste and smell, and a preparation method thereof. The spleen-invigorating the qi-replenishing particle of the invention comprises raw material drugs and auxiliary materials with a mass ratio of (4:1)-(6:1), wherein the raw material drugs comprise the following components by mass: 18-22 parts of mix-fried astragalus; 5-6.5 parts of radix codonopsis; 9-11 parts of mix-fried licorice; 5-6.5 parts of angelica; 5-6.5 parts of fried atractylodes; 5-6.5 parts of cimicifuga foetida; 5-6.5 parts of radix bupleuri; 5-6.5 parts of tangerine peel; 1.5-2.5 parts of ginger; 3.5-4.5 parts of jujube; the auxiliary materials comprise lactose and dextrin, wherein lactose accounts for 50%-90% of the total mass of the auxiliary materials, and the balance of dextrin; or in the auxiliary materials, lactose is used instead of lactose and dextrin.

Description

Technical field [0001] The invention relates to a composition mainly derived from plants and a preparation method thereof. Background technique [0002] The prescription of Buzhong Yiqi Granules was taken from the Buzhong Yiqi Decoction created by Li Dongheng during the Jin and Yuan Dynasties (the prescription was first published in "Spleen and Stomach Theory"). The product is composed of Astragalus, Codonopsis, Licorice, Atractylodes, Angelica, Tangerine Peel, Cimicifuga, Bupleurum, Dried Ginger, and Jujube. Among them, Astragalus replenishes qi for the monarch, licorice nourishes the middle for the minister, Atractylodes macrocephala for the spleen, Angelica replenishes the middle, and tangerine peel replenishes the qi, all of which are adjuvants, and cohosh and Bupleurum are the inducers of Qingyang. This product is widely used in clinical medicine, medicine, gynecology, and pediatrics. It has the functions of invigorating the middle and replenishing qi and raising the sun. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P1/00A61P15/00
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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