Method for automatically transferring material drug freeze-drying tray to freeze drier ply

A lyophilizer and API technology, which is used in the preliminary treatment, drying, transportation and packaging to promote the drying of solid materials, can solve the problems of tray contamination and adverse sterility, and achieve high sterility and ensure no Bacterial effect

Inactive Publication Date: 2012-01-04
SHANGHAI TOFFLON SCI & TECH CO LTD
View PDF5 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Compared with the traditional method, the latter method has greatly improved the maintenance of sterility, but there is still a lot of manual intervention in the process of l

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for automatically transferring material drug freeze-drying tray to freeze drier ply
  • Method for automatically transferring material drug freeze-drying tray to freeze drier ply
  • Method for automatically transferring material drug freeze-drying tray to freeze drier ply

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] In order to make the present invention more comprehensible, a preferred embodiment is described below in detail with the accompanying drawings.

[0017] Combine figure 1 , The present invention provides a method for automatically transferring the freeze-drying tray of APIs to the layer of the freeze-drying machine, and the steps are:

[0018] Step 1. Put the tray 1 into the automatic dish washer 2 located in the clean room and clean it;

[0019] Step 2. Transfer the cleaned tray 1 to the tray sterilization tunnel oven 4 through the chain plate 3 for sterilization and drying;

[0020] Step 3. After the tray 1 is sterilized and dried, the automatic tray-in / out device 8 moves along the track 6 to the sterilization tunnel oven 4 for docking, and the tray 1 is protected by the A-level unidirectional submerged protection device 5 located above the docking area. take out;

[0021] Step 4. Combine figure 2 , The automatic disk access device 8 moves along the track 6 to the door of the ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a method for automatically transferring a material drug freeze-drying tray to a freeze drier ply. The method is characterized by comprising the following steps: taking the tray out of a tray sterilizing tunnel oven by using an automatic tray feeding and discharging device; putting the tray into a freeze drier, putting while feeding until all the plies of the freeze drier are filled; and then starting the freeze drier to carry out freeze-drying. The method provided by the invention has the advantages of solving the high-risk problem of manually tray transferring or tray loading in the traditional method, guaranteeing that the whole tray transferring process is automatically completed under the asepsis protection state and conforming to the requirements of international pharmaceutical industry CGMP (current good manufacturing practice), and has high sterility.

Description

Technical field [0001] The invention relates to a method for automatically transferring a raw material drug freeze-dried tray to the layer of a freeze dryer, so that a series of aseptic operations of the raw material drug freeze-drying tray are automatically completed under the control of the aseptic process from the start of cleaning. Background technique [0002] The traditional process of transferring the lyophilized API tray to the layer of the lyophilizer is as follows: First, the operator removes the cleaned, sterilized and dried API lyophilized tray (hereinafter referred to as the tray) from the sterilizer, and then The tray is filled with the material liquid, and then the tray filled with the material liquid is manually transported to the layer of the freeze dryer, and finally the freeze-drying box door is closed to freeze-dry the API. [0003] The typical freeze-drying steps of sterile APIs are as follows: first, the cleaned, sterilized and dried trays are transported by ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): F26B1/00B67D99/00
Inventor 郑效东
Owner SHANGHAI TOFFLON SCI & TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap