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Single phase liquid refrigerant cryoablation system with multitubular distal section and related method

A liquid refrigeration and refrigerant technology, which is used in catheters, cooling surgical instruments, and parts of surgical instruments, etc., can solve the problems of prolonging the pre-cooling time of instruments, difficult to manufacture, and unable to effectively heat the freezing probe.

Inactive Publication Date: 2012-03-21
CRYOMEDIX
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] However, the use of subcritical cryogens in cryoablation systems is extremely challenging
Specifically, once nitrogen passes its critical point (approximately 8 times), the density of nitrogen changes significantly - leading to the need for extended instrument pre-cooling times
The heat capacity is only high near the critical point, and the efficiency of the system is low at higher temperatures due to the long pre-cooling time
Additionally, the system cannot effectively heat (or thaw) cryoprobes
Also, subcritical refrigerant systems require custom cryopumps, which are more difficult to manufacture

Method used

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  • Single phase liquid refrigerant cryoablation system with multitubular distal section and related method
  • Single phase liquid refrigerant cryoablation system with multitubular distal section and related method
  • Single phase liquid refrigerant cryoablation system with multitubular distal section and related method

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Embodiment Construction

[0039] Before the present invention is described in detail, it should be understood that this invention is not limited to the specific modifications set forth herein, that various changes and modifications can be made to the invention, and equivalents can be made without departing from the spirit and scope of the invention. being replaced. Those of ordinary skill in the art will appreciate, upon reading this disclosure, that each of the various embodiments described and exemplified herein has a function independent of any other implementations without departing from the scope or spirit of the invention. Features of the example or individual components and features that can be combined therewith. In addition, many modifications may be made to adapt a particular situation, material, composition of matter, process, process(s) or step(s) to the objective(s), spirit or scope of the invention. All such modifications are within the scope of the claims set forth herein.

[0040] The...

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Abstract

Single phase liquid refrigerant cryoablation systems and methods are described herein. The cryoablation systems drive liquid cryogen or refrigerant along a closed fluid pathway without evaporation of the liquid cryogen. A cryoprobe includes a distal energy delivery section to transfer energy to the tissue. A plurality of cooling microtubes positioned in a distal section of the cryoprobe transfer cryogenic energy to the tissue. The plurality of microtubes in the distal section are made of materials which exhibit flexibility at cryogenic temperature ranges, enabling the distal section of the cryoprobe to bend and conform to variously shaped target tissues.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of Application No. 61 / 167,057, filed April 6, 2009, entitled "Cryogenic System for Improved Cryoablation Treatment." technical field [0003] The present invention relates to cryoablation systems for treating biological tissue, and more particularly to cryoablation probes employing liquid cryogens, and cryotherapy probes with multi-tube distal ends. Background technique [0004] Cryoablation involves the proper freezing of the target biological tissue to be treated using extremely low temperature and complex cooling systems. Most of these systems employ cryoprobes or catheters of a specific shape and size that are designed to contact selected portions of tissue without adversely affecting any nearby healthy tissue or organs. Extreme freezing is achieved with some type of cryogen introduced through the distal end of the cryoprobe. This part of the cryoprobe must be in direct thermal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/02
CPCA61B18/02A61B2018/0212A61B2018/0262
Inventor 阿莱克谢·巴布金彼得·利特拉普威廉·尼达姆巴龙·尼达姆
Owner CRYOMEDIX