Pharmaceutical composition for lowering blood sugar

A composition and blood sugar-lowering technology, applied in the field of biomedicine, can solve problems such as impaired insulin secretion, and achieve the effects of less recurrence, lower production costs, and a shorter course of treatment

Inactive Publication Date: 2012-06-13
如东县新店镇农田排灌服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, β-cell dysfunction results in impaired insulin secretion that is progressively worse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A pharmaceutical composition for lowering blood sugar, which is prepared from the following weight ratio raw materials:

[0026] Asparagus 20, Scutellaria 18, Cinnamon 18, Angelica 16, Anemarrhena 15, Burdock Root 12, Licorice 12, Astragalus 10, Atractylodes Macrocephala 9, White Peony 8, Wumei 7, Pueraria 6, Rehmanniae 6, Schisandra 4, Ginseng 4.

[0027] The preparation method of the above-mentioned pharmaceutical composition includes the following steps: take each weight of the above-mentioned raw material medicine for use; add 3 times the amount of water to decoct for 2 hours, filter and collect the filtrate, and concentrate the filtrate into an extract with a density of 1.1g / ml; 60°C After drying, the powder is crushed to 100 mesh, filled into capsules, and sterilized to prepare a capsule preparation.

[0028] Dosage form and usage: This prescription is a capsule dosage form, three times a day, half an hour before meals, 2 capsules each time, 0.5g each capsule, two weeks ...

Embodiment 2

[0030] Animal pathology experiment

[0031] Test animals: 50 Wistar rats, male, 180-200g. After the rats were adapted to feeding for 5 days in the animal room, 10 rats were randomly selected as the normal control group and fed with ordinary maintenance feed. High-sugar and high-fat feed formula: rat basic feed 68%, sucrose 10%, egg yolk powder 9%, lard 8%, cholesterol 1%, bile salt 0.2%.

[0032] Implementation mode: The remaining 40 were fed with high-sugar and high-fat feed for 4 weeks. After 4 weeks of fasting for 18 hours, the rats were given an intravenous injection of 20 mg / Kg of streptozotocin (STZ) once every two days. After two use, the model was successful if the blood glucose and blood lipids remained high. Thirty rats successfully modeled were selected and randomly divided into 3 groups, each with 10 rats, namely the model group (no drugs are administered), the drug group of Example 1 of the present invention, 10 mg / Kg, and the control drug group: Gliclazide administe...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for lowering blood sugar, which is prepared from the following raw materials according to a weight ratio: 20 of radix asparagi, 18 of radix scutellariae, 18 of cinnamon, 16 of angelica, 15 of rhizoma anemarrhenae, 12 of radix bardanae, 12 of licorice, 10 of astragalus mongholicus, 9 of atractylis ovata, 8 of radix paeoniae, 7 of prunus mume, 6of kudzu root, 6 of prepared rehmannia root, 4 of shizandra berry and 4 of ginseng. The pharmaceutical composition has a good curative effect, high clinical treatment effective rate, no recurrence after healing and a simple process, reduces the production cost and greatly alleviates the economic burden of the patients.

Description

Technical field [0001] The invention belongs to the technical field of biomedicine, and specifically relates to a pharmaceutical composition for lowering blood sugar and a preparation method thereof. Background technique [0002] Diabetes is caused by various pathogenic factors such as genetic factors, immune dysfunction, microbial infections and their toxins, free radical toxins, mental factors, etc., which act on the body to cause hypofunction of islets, insulin resistance, etc., and cause sugar, protein, fat, and water. A series of metabolic disorder syndromes, such as electrolytes and electrolytes, are clinically characterized by hyperglycemia. Typical cases may have manifestations of polyuria, polydipsia, polyphagia, weight loss, etc., that is, "three more and one less" symptoms. Once diabetes (blood sugar) Poor control can cause complications, leading to failure of the kidneys, eyes, feet and other parts, and there is no cure. [0003] The sugar in the blood is called blood ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P3/10
Inventor 宋炳红张继述
Owner 如东县新店镇农田排灌服务有限公司
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