Separation and purification process of chinoline with high purity

Abstract

The invention relates to a separation and purification process of chinoline with high purity. The process comprises the following steps of: (1) inputting coarse chinoline into a rectifying tower, carrying out decompress rectify, carrying out sampling analysis per hour, and cutting fractions to a middle slot A when the content of the chinoline rises up to more than 90%; (2) re-inputting materials which are in the middle slot A into the rectifying tower for secondary rectify, carrying out sampling analysis per hour, cutting components to an appointed middle slot B when the content of the chinoline rises up to more than 98%, collecting into an end product slot when the content of the chinoline directly rises up to 99%, and continuously cutting into the middle slot B after the content of the chinoline is lower than 99%; and (3) inputting materials which are in the middle slot B into the rectifying tower for third-time rectify, carrying out sampling analysis per hour, and collecting end products when the content of the chinoline rises up to 99%. Compared with the prior art, the process has the advantages of being low in cost, capable of industrial production and the like.

Description

technical field [0001] The invention relates to a quinoline purification process, in particular to a high-purity quinoline separation and purification process. Background technique [0002] In industry, quinoline is mainly extracted or chemically synthesized from coal tar wash oil. Coal tar extraction is a traditional method. Coal tar is produced through a series of steps such as acid and alkali treatment, rectification purification or recrystallization to produce quinoline products. The chemical synthesis method usually uses aromatic amine compounds such as aniline or anthranilic acid as starting materials, and undergoes addition reaction with unsaturated aldehydes or ketones to obtain quinoline compounds. [0003] The traditional process of extracting quinoline from coal tar wash oil inevitably contains impurities such as indole, and the content of quinoline is generally below 97%. Synthetic process, although the product purity can reach 99%, but the production cost is v...

AI Technical Summary

Problems solved by technology

Synthetic process, although the product purity can reach 99%, but the production cost is very high and cannot be industrialized