Viral aerosol collecting and enriching instrument

Abstract

The invention relates to a viral aerosol collecting and enriching instrument which comprises a framework, a gas feeder, a gas outlet unit nozzle and a collection unit pipe. The gas feeder is used for collecting gas samples to be detected and inputting the gas samples to the gas outlet unit nozzle through a gas pipe. The gas outlet unit nozzle and the collection unit pipe are both arranged on the framework, the collection unit pipe is detachably arranged below the gas outlet unit nozzle, and testing liquid with virus capturing immunomagnetic beads is arranged on the collection unit pipe. The gas samples are sprayed into the collection unit pipe through the gas outlet unit nozzle in a rotary mode. The testing liquid absorbs aerosol contained in the gas to be detected, and virus carried by the gas to be detected is captured through the virus immunomagnetic beads. According to the invention, bio-aerosol in the air can be effectively captured, and virus microbial samples can be specifically enriched, therefore, the viral aerosol collecting and enriching instrument is especially suitable for monitoring virus pathogens in environmental air.

Description

technical field [0001] The invention relates to a viral aerosol collection and enrichment device, in particular to an integrated device for effectively collecting biological aerosols in ambient air and integrating virus enrichment technology for subsequent virus detection. Background technique [0002] At present, most of the epidemics of infectious diseases are mainly caused by virus infection, and the virus infection with the respiratory tract as the main transmission route is very easy to spread rapidly in a short period of time and lead to serious public health incidents due to its convenient transmission mode. In recent years, SARS The serious health hazards and international concerns caused by the infection and spread of highly pathogenic avian influenza and the new type A H1N1 influenza virus are typical examples; the spread of virus-like bioterrorism factors through aerosol is also the focus of anti-terrorism experts. Guard content. In addition, non-respiratory vi...

AI Technical Summary

Problems solved by technology

[0005] 2) The collection efficiency of aerosol particles is low, especially the collection efficiency of aerosol particles at the submicron level;

[0006] 3) Insufficient particle removal and concentration techniques in collection media lead to inefficiencies;

[0008] 5) Poor operability for virus monitoring, or lack of on-site portability settings

Due to the characteristics of nano-scale particles of viruses and the high variability of pathogens such as influenza viruses, the concentration and discharge of viruses in the local respiratory tract of different viruses are different, and the detection methods of different viruses are different. There is a lack of systematic and targeted research, and the corresponding sample collection devices do not have the integration of virus enrichment technology. The sensitivity of virus detection needs to be improved, and the connection with subsequent detection technologies also needs to be improved. No air sampling device that integrates virus collection and enrichment has been seen.

At the same time, based on the environmental requirements of air virus monitoring, the existing biological samplers lack portability, simplicity and specificity in terms of the characteristics of relatively closed and narrow spaces such as vehicles, biosafety laboratories or animal farms, making sampling The device does not meet the actual requirements

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