Veterinary pharmaceutical composition and method (alternatives) for the prophylaxis and treatment of diseases of the gastrointestinal tract and intoxications of diverse etiology in animals

Abstract

A veterinary pharmaceutical composition for treating diseases of the gastrointestinal tract and intoxications of diverse etiology in animals comprises, as the active components, hydrolyzed lignin and a prebiotic from the following group: lactulose, fructooligosaccharides, galacto-saccharides and inulin, and is in a form suitable for use in the composition of a mixture with combined feed, with a lignin content of from 30 to 95% by mass and a prebiotic content of from 5 to 50% by mass, in the form of powder or granules. The method for the prophylaxis and treatment of intoxications of diverse etiology, including mycotoxicoses, in animals, including birds, envisages that the animal will receive the above-mentioned veterinary pharmaceutical composition mixed with feed in a dosage of from 2 to 4.5 kg of the preparation per ton of combined feed, proportional to the content of mycotoxins in the combined feed. The method for the prophylaxis and treatment of diseases of the gastrointestinal tract, including dyspepsia, gastroenteritis, enteritis, colitis, hepatitis and hepato-dystrophy, including in a toxic form, in animals, including cattle and pigs, envisages that the animal will receive the veterinary pharmaceutical composition according to claim 1 30 +- 10 minutes prior to feeding, perorally individually or in a group method with water for watering or with the feed, 1 to 2 times per day in a dosage of from 0.2 to 0.3 g / kg of the mass of the animal. This ensures an increase in the effectiveness of the treatment and elimination of the above-mentioned defects in the use of hydrolyzed lignin, activated carbon and other generally known sorbents. At the same time, the joint use of lignin with a prebiotic as a means for the prophylaxis and treatment of animals makes it possible to produce a result in the form of a set of positive effects: minimization of side effects from the use of a sorbent; restoration of homeostasis in the gastrointestinal tract; and normalization of the metabolism indices, this finally resulting in a qualitative increase in the zootechnical and economic indices of animal husbandry.

Description

technical field [0001] The present invention relates to the field of pharmacy, more specifically to the field of veterinary medicine, which can be used to prevent and treat gastrointestinal diseases and various toxic diseases in animals. Animals include poultry, cattle and pigs, and various toxic diseases include fungal poisoning, digestive Dysentery, gastroenteritis, enteritis, colitis, hepatitis and acute yellow liver atrophy and toxic diseases. Background technique [0002] Under the conditions of livestock intensification and farm economic development, along with improvements in animal breeds and productivity, we should pay special attention to improving the survival rate of animal pups while increasing animal productivity. Many diseases, first of all gastrointestinal diseases (mainly acute and chronic dyspepsia) increase the mortality rate of young livestock (including calf and piglets). These livestock diseases are pervasive and cause substantial economic losses, ofte...

AI Technical Summary

Problems solved by technology

[0014] However, while having significant positive properties on toxin adsorption, the above-mentioned pharmaceutical composition also has considerable side effects on animal husbandry: adding sufficient and effective drugs of this type to absorb toxins in the ration will also adsorb some bioactive components (vitamins) in the feed simultaneously. , essential amino acids, minerals, etc.), which can adversely affect the production indicators of animal and poultry farming

The formulation of enteric sorbents as aqueous suspension formulations is hardly suitable for widespread adoption in the livestock sector

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