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Anti-adhesion material

An anti-adhesion and covering layer technology, applied in thin material processing, medical science, surgical medicine, etc., can solve the problems of poor operability and achieve the effects of improved adhesion, excellent anti-adhesion performance, and full decomposability

Active Publication Date: 2012-09-12
KAWASUMI LABORITORIES INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] In the conventional anti-adhesion materials disclosed in Patent Documents 1 and 2, since water-soluble polymers such as hyaluronic acid are hydrophilic (water-soluble), there are problems such as difficulty in handling with wet tweezers during surgery, etc. Problem with very poor workability after wet

Method used

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Experimental program
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Effect test

no. 1 approach

[0058] figure 1 It is a schematic diagram for explaining the anti-adhesion material 1 of the first embodiment, figure 1 (a) is a perspective view of the anti-adhesion material 1, figure 1 (b) Its partial enlarged cross-sectional view. In addition, for easy understanding of the invention, in figure 1 (a) and figure 1 In (b), the layer thickness of the base layer 10 and the layer thicknesses of the first covering layer 20 and the second covering layer 30 relative to the base layer 10 are shown with a certain degree of exaggeration.

[0059] Such as figure 1 As shown, the anti-adhesion material 1 of the first embodiment includes a sheet-shaped base layer 10, a first covering layer 20 disposed on one side of the base layer 10, and a second covering layer 20 disposed on the other side of the base layer 10. Layer 30.

[0060] The base layer 10 is made of a water-soluble polymer. As the water-soluble polymer, polysaccharides, proteins, or synthetic polymers can be preferably u...

no. 2 approach

[0083] figure 2 It is a schematic diagram for demonstrating the anti-adhesion material 2 of 2nd Embodiment. figure 2 (a) is a perspective view of the anti-adhesion material 2, figure 2 (b) is a partially enlarged cross-sectional view of the anti-adhesion material 2 . In addition, for easy understanding of the invention, in figure 2 (a) and figure 2 In (b), the layer thickness of the base layer 10 and the layer thickness of the covering layer 22 with respect to the base layer 10 are shown with some degree of exaggeration. In addition, in figure 2 in, with figure 1 The same symbols are used for the same components, and detailed description thereof will be omitted.

[0084] The anti-adhesion material 2 of the second embodiment basically has a structure very similar to that of the anti-adhesion material 1 of the first embodiment, but differs from the anti-adhesion material 1 of the first embodiment in that the covering layer is arranged only on one side of the base lay...

no. 3 approach

[0093] image 3 It is a schematic diagram for demonstrating the anti-adhesion material 3 of 3rd Embodiment. image 3 (a) is a perspective view of the anti-adhesion material 3, image 3 (b) is a partially enlarged cross-sectional view of the anti-adhesion material 3 . In addition, for easy understanding of the invention, in image 3 (a) and image 3 In (b), the layer thickness of the base layer 12 and the layer thicknesses of the first covering layer 20 and the second covering layer 30 relative to the base layer 12 are shown with a certain degree of exaggeration. In addition, in image 3 in, with figure 1 The same symbols are used for the same components, and detailed description thereof will be omitted.

[0094] The anti-adhesion material 3 of the third embodiment basically has a structure very similar to that of the anti-adhesion material 1 of the first embodiment, but differs from the anti-adhesion material 1 of the first embodiment in that an antibacterial agent is ad...

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Abstract

Disclosed is an anti-adhesion material which exhibits more excellent handling properties when get wet in comparison to conventional anti-adhesion materials, while having sufficient in vivo degradability and excellent anti-adhesion properties. Specifically disclosed is an anti-adhesion material (1) which comprises: a sheet-like base layer (10) that contains a water-soluble polymer (for example, pullulan); a first coating layer (20) that is arranged on one surface of the base layer (10) and contains an aliphatic ester; and a second coating layer (30) that is arranged on the other surface of the base layer (10) and contains an aliphatic ester. The first coating layer (20) and the second coating layer (30) are formed to have an optical thickness of 27 nm or more but less than 160 nm.

Description

technical field [0001] This invention relates to anti-blocking materials. Background technique [0002] As an existing anti-adhesion material for reducing the adhesion of living tissue due to surgery, trauma, etc., anti-adhesion materials using water-soluble polymers such as hyaluronic acid are known (for example, refer to Patent Document 1 ,2). [0003] According to the conventional anti-adhesion materials, since water-soluble polymers such as hyaluronic acid are used, the anti-adhesion materials are excellent in biocompatibility and biodegradability in vivo. [0004] In addition, as other existing anti-adhesion materials, there is known an anti-adhesion material (such as , refer to Patent Documents 3-5). [0005] prior art literature [0006] patent documents [0007] Patent Document 1: Japanese National Publication No. 5-508161 [0008] Patent Document 2: Japanese National Publication No. 6-508169 [0009] Patent Document 3: Japanese Patent Laid-Open No. 2003-12623...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/00A61L15/64
CPCA61L31/10A61L31/148A61P31/04A61P41/00Y10T428/24942Y10T428/265Y10T428/31786
Inventor 谷彻神谷纯広向井智和
Owner KAWASUMI LABORITORIES INC
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