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Liniment for treating dermatophytosis and preparation method thereof

A beriberi and sycamore technology, applied in the field of liniment for treating beriberi and its preparation, can solve the problems of easy recurrence of beriberi, skin irritation, unpleasant smell, etc., and achieve a pleasant smell, increased antibacterial spectrum, and production cost. low effect

Active Publication Date: 2012-09-19
迈科凯普(杭州)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Current beriberi medicine products all have certain anti-ringworm effect, but the beriberi after curing easily recurs; Some products also have certain irritation to skin; Some product cost is higher, and retail price is more expensive; Some product smell bad smell

Method used

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  • Liniment for treating dermatophytosis and preparation method thereof
  • Liniment for treating dermatophytosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A kind of liniment for treating beriberi is prepared by the following steps:

[0025] (1) Take 300g of sycamore leaves, wash them, dry them in the air, crush them, soak them in 5000ml of 50% ethanol aqueous solution for 7 days, then filter them, concentrate the filtrate to extract, and get 80g of dry extracts, which are the leaves of sycamores Alcoholic extract;

[0026] (2) Take 80g of the alcohol extraction extract of the leaves of the sycamore tree, dissolve it with an appropriate amount of 50% ethanol aqueous solution and set aside; take 10g of ciclopiroxamide, dissolve it with an appropriate amount of 50% ethanol aqueous solution and add it to the alcohol of the leaves of the sycamore tree Add 200ml of polyethylene glycol to the ethanol solution of the extract, and dilute to 1000ml with 50% ethanol aqueous solution, stir well to obtain the sycamore leaf · ciclopiroxamide liniment.

Embodiment 2

[0028] A kind of liniment for treating beriberi is prepared by the following steps:

[0029] (1) The preparation method of the alcohol-extracted extract of sycamore leaves is the same as the step (1) of Example 1;

[0030] (2) Take 50g of the alcohol-extracted extract of the leaves of the sycamore tree, dissolve it with an appropriate amount of 50% ethanol aqueous solution and set aside; take 10g of ciclopiroxamide, dissolve it with an appropriate amount of 50% ethanol aqueous solution and add it to the alcohol of the leaves of the sycamore tree Add 200ml of polyethylene glycol to the ethanol solution of the extract, and dilute to 1000ml with 50% ethanol aqueous solution, stir well to obtain the sycamore leaf · ciclopiroxamide liniment.

Embodiment 3

[0032] A kind of liniment for treating beriberi is prepared by the following steps:

[0033] (1) The preparation method of the alcohol-extracted extract of sycamore leaves is the same as the step (1) of Example 1;

[0034] (2) Take 100g of the alcohol-extracted extract of the leaves of the sycamore tree, dissolve it with an appropriate amount of 50% ethanol aqueous solution and set aside; take 10g of ciclopiroxamide, dissolve it with an appropriate amount of 50% ethanol aqueous solution and add it to the alcohol of the leaves of the sycamore tree Add 200ml of polyethylene glycol to the ethanol solution of the extract, and dilute to 1000ml with 50% ethanol aqueous solution, stir well to obtain the sycamore leaf · ciclopiroxamide liniment.

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Abstract

The invention discloses a liniment for treating dermatophytosis and a preparation method thereof. The liniment contains chinar leaf extract and ciclopirox olamine, the weight ratio of which is (5 to 10):1; the chinar leaf extract is the alcohol extract of chinar leaves, and is prepared by the following steps: chinar leaves are soaked in ethanol solution for 5 to 10 days, and is then filtered, filtrate is concentrated into extract, and thereby the alcohol extract of chinar leaves is obtained. Since the chinar leaf extract and the ciclopirox olamine are compatibly used, the anti-dermatophyte spectrum of the liniment is broadened, the antibacterial effect of the liniment is enhanced, and moreover, cured dermatophytosis cannot easily recur. The liniment does not have peculiar smell, and the smell is fragrant and pleasant; the action of the liniment is mild, and the liniment does not have any irritation on skin.

Description

technical field [0001] The invention relates to a liniment for treating beriberi and a preparation method thereof. Background technique [0002] Athlete's foot is a very common fungal infectious skin disease, commonly known as athlete's foot. The average incidence rate in my country is nearly 30%, and in some high-incidence areas such as the southern and eastern coastal areas, the incidence rate is even as high as 60%. In some special occupations (such as miners, etc.), the incidence rate can reach 80-100%. [0003] The harm of beriberi cannot be ignored. It not only affects daily life but also affects personal image, and it is easy to infect other parts of the body, and can cause secondary infection in severe cases. [0004] Because beriberi has a high incidence rate in my country, the potential market capacity of medicines for treating beriberi is very large. There are many beriberi medicine products available, among which the more famous ones are: Daknin, Lanmisil, Jin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P17/00A61P31/10A61K31/4412A61K127/00
Inventor 何刚
Owner 迈科凯普(杭州)生物科技有限公司
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