Optic disc projection location method synthesizing vascular distribution with video disc appearance characteristics

Abstract

The invention discloses an optic disc projection location method synthesizing vascular distribution with video disc appearance characteristics, which comprises the following steps of: (1) extracting an interest retina fundus image region by use of a mask operation; (2) carrying out normalization enhancement on a fundus image based on an image observation model; (3) achieving extraction and segmentation of the fundus image by using a non-vascular structure inhibition operator and combining with a hysteresis multi-threshold processing technology; (4) setting a vertical window of double main blood vessel width to slide on a blood vessel segmentation image along the horizontal direction and calculating a vascular distribution degree D(x) at each horizontal position x to obtain a distribution degree curve of a horizontal projection, wherein the minimum value point of the curve is determined to be optic disc horizontal coordinate xod; (5) setting a rectangular window side length of which is equal to the optic disc diameter to slide up and down at the horizontal coordinate xod, estimating local region brightness IN(xod, y) and edge gradient information gN(xod, y) respectively, drawing a vertical projection curve reflecting a change of a characteristic value f(y)=IN(xod, y)*gN(xod, y), wherein a maximum value point of the curve is optic disc vertical coordinate yod. The method has a simple algorithm, a high success rate and excellent robustness.

Description

technical field

[0001] The invention relates to a method for automatically locating an optic disc in a retinal fundus image, in particular to an optic disc projection positioning method that integrates the distribution of blood vessels and the appearance characteristics of the optic disc. Background technique

[0002] The optic disc is one of the main physiological structures of the retina. The optic nerve and blood vessels enter the eye from this area and radiate to the periphery. In the retinal fundus image, it appears as a round bright yellow area and contains a large number of thick blood vessels. Researchers have always paid great attention to the automatic positioning of the optic disc, because the accurate positioning of the optic disc is beneficial to the diagnosis of fundus lesions, for example: many optic disc segmentation algorithms need to give the initial seed point in advance; The distance is approximately constant, and when the location of the optic disc is de...

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