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Medicine composition for treating depression and preparation method thereof

A composition and depression technology, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problems of difficulty in determining the main active ingredients, slow clinical efficacy, complex drug ingredients, etc. Easy to take, good curative effect, no toxic and side effects

Inactive Publication Date: 2013-02-27
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Because traditional Chinese medicine contains multiple ingredients, it can act on the body at multiple targets, and regulate each system as a whole to achieve the purpose of treatment. The curative effect is usually slow, and its quality control is also difficult during industrialization. Therefore, it is necessary to use modern technology to extract and separate each single traditional Chinese medicine to determine the active ingredients or to formulate the ingredients to improve the clinical efficacy and clarify the mechanism of action. Control product quality

Method used

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  • Medicine composition for treating depression and preparation method thereof
  • Medicine composition for treating depression and preparation method thereof
  • Medicine composition for treating depression and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1:: A pharmaceutical composition for treating depression, which is composed of saikosaponin, turmeric volatile oil and pachyrhiza in the following weight ratios: 1 part of saikosaponin, 1 part of turmeric volatile oil and 2 parts of pachyman.

[0031] The pharmaceutical dosage forms are tablets, capsules, powders, granules, syrups, oral liquids, freeze-dried powder injections or injections, and the present embodiment takes tablets as an example.

[0032] A method for preparing a pharmaceutical composition for the treatment of depression, comprising the following steps:

[0033] S1: Preparation of raw materials: preparation of saikosaponin, turmeric volatile oil and pachyrhin;

[0034] S2: Weighing raw materials: Weighing 100g of saikosaponin, 100g of turmeric volatile oil, and 200g of polysaccharide;

[0035] S3: Inclusion of raw materials: Include and grind the turmeric volatile oil that has been weighed with 200g of β-cyclodextrin and pass it through 100 mes...

Embodiment 2

[0042] Example 2: A pharmaceutical composition for treating depression, which is composed of saikosaponin, turmeric volatile oil and pachymane in the following weight ratio: 1 part of saikosaponin, 2 parts of turmeric volatile oil, and 2 parts of pachymane polysaccharide.

[0043] The pharmaceutical dosage forms are tablets, capsules, powders, granules, syrups, oral liquids, freeze-dried powder injections or injections, and the present embodiment takes tablets as an example.

[0044] A method for preparing a pharmaceutical composition for the treatment of depression, comprising the following steps:

[0045] S1: Preparation of raw materials: preparation of saikosaponin, turmeric volatile oil and pachyrhin;

[0046] S2: Weigh raw materials: weigh 100g of saikosaponin, 200g of turmeric volatile oil, and 200g of polysaccharide;

[0047] S3: Inclusion of raw materials: Include the weighed turmeric volatile oil with 400g of β-cyclodextrin, grind it finely, and pass it through 100...

Embodiment 3

[0051] Example 3 : a pharmaceutical composition for treating depression, which is composed of saikosaponin, turmeric volatile oil and pachyrhiza in the following weight ratios: 1 part of saikosaponin, 1 part of turmeric volatile oil and 3 parts of pachycarphan.

[0052] The pharmaceutical dosage forms are tablets, capsules, powders, granules, syrups, oral liquids, freeze-dried powder injections or injections, and the present embodiment takes tablets as an example.

[0053] A method for preparing a pharmaceutical composition for the treatment of depression, comprising the following steps:

[0054] S1: Preparation of raw materials: preparation of saikosaponin, turmeric volatile oil and pachyrhin;

[0055] S2: Weighing raw materials: Weighing 100g of saikosaponin, 100g of turmeric volatile oil, and 300g of polysaccharide;

[0056] S3: Inclusion of raw materials: Include the weighed turmeric volatile oil with 400g of β-cyclodextrin, grind it finely, and pass it through 100 mesh...

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Abstract

The invention discloses a medicine composition for treating depression and a preparation method thereof. The medicine composition comprises the following ingredients in parts by weight: 1-2 parts of saikosaponin, 1-2 parts of radix curcumae volatile oil and 1-3 parts of pachymaran. The preparation method of the medicine composition for treating depression comprises four steps of raw material preparation, raw material weighing, raw material inclusion and medicine mixing and forming. The medicine composition is prepared by combining active ingredients of natural medicinal raw materials or extracts of the active ingredients of the medicinal raw materials, and has the advantages that the medicine composition has good curative effects and no toxic or side effects, is not easy to generate tolerance, is universally suitable for depression patients, etc. Being prepared from the extracts of the active ingredients, the medicine composition is taken without decoction, can be applied to the patients by oral administration, suction or parenteral administration, can be prepared into tablets, capsules, powder, granules, syrup or oral liquid and the like, and is convenient to carry and take.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating depression and a preparation method thereof, in particular to a pharmaceutical composition prepared from extracts of Chinese medicinal materials and a preparation method thereof. Background technique [0002] Depression is a common mood disorder, which can be caused by various reasons. The main clinical feature is marked and persistent low mood, and the low mood is not commensurate with the situation. In severe cases, suicidal thoughts and behaviors may appear. Most cases have a tendency to relapse, and most of each attack can be relieved, and some may have residual symptoms or become chronic. [0003] The pathological and pathogenesis of depression has not been clearly explained in modern western medicine, but many studies have shown that both central nervous system dysfunction and exogenous events can cause depression. It is precisely because of long-term central nervous system dysfun...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/24A61K31/715
Inventor 文跃强贾波胡静彭腾杨洁陈姣冯跃李果
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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