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Composition with penetration enhancing effect as well as preparation method and application thereof

A composition and penetration-promoting technology, applied in the field of natural product extraction, can solve problems such as unsatisfactory effects, and achieve the effects of improving skin quality and promoting penetration and absorption

Active Publication Date: 2013-03-13
海南艾纳香生物科技发展股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as eucalyptus oil, menthol, clove oil, etc. have begun to be used as penetration enhancers in cosmetics and pharmaceuticals, but the effect is not ideal

Method used

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  • Composition with penetration enhancing effect as well as preparation method and application thereof
  • Composition with penetration enhancing effect as well as preparation method and application thereof
  • Composition with penetration enhancing effect as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 composition of the present invention

[0025] Take 10kg of Ai Naxiang, soak Ai Naxiang in water whose weight is 12 times of the weight of Ai Naxiang for 3 hours, extract by steam distillation for 8 hours, and separate and obtain 1 mL of Ainaxiang's volatile oil. The water extract was obtained by filtration, and the water extract was centrifuged at 4000 r / min for 7 minutes to obtain a supernatant, and the supernatant was dried to dryness to obtain 1.8 kg of water extract of Ai Naxiang.

[0026] Get 5kg of patchouli, soak the patchouli in water whose weight is 12 times the weight of the patchouli for 6 hours, extract by steam distillation for 8 hours, separate and obtain 0.5mL of the volatile oil of patchouli, filter to obtain water For the extract, the water extract was centrifuged at 4000 r / min for 7 minutes to obtain a supernatant, and the supernatant was dried to dryness to obtain 0.8 kg of a water extract of Patchouli.

[0027] Mix th...

Embodiment 2

[0028] The preparation of embodiment 2 compositions of the present invention

[0029] According to the same manner as in Example 1, the composition with permeation-promoting effect of the present invention was obtained, except that 20kg of Ainaxiang and 1kg of Patchouli were used.

Embodiment 3

[0030] The preparation of embodiment 3 compositions of the present invention

[0031] According to the same manner as in Example 1, the composition with permeation-promoting effect of the present invention was obtained, except that 1kg of Ainaxiang and 10kg of Patchouli were used.

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Abstract

The invention relates to a composition with a penetration enhancing effect, which is prepared from the following substances in parts by weight: 1-20 parts of blumea balsamifera and 1-10 parts of pogostemon cablin. The invention further relates to a preparation method of the composition. The preparation method of the composition is simple and feasible and is convenient for industrial production. The invention further relates to an application of the composition. The composition disclosed by the invention has a good penetration enhancing function and small irritation, has the effects of diminishing inflammation and relieving pain, and removing scars and promoting tissue regeneration, and can be widely applied to various drugs and cosmetics.

Description

technical field [0001] The invention relates to the field of extraction of natural products, in particular, the invention relates to a composition with an effect of promoting penetration and its preparation method and application. Background technique [0002] The skin is the barrier between the human body and the external environment. Under normal circumstances, it is difficult for foreign substances to enter the blood through the skin. Therefore, when preparing skin care products and medicines, it is often necessary to add some penetration enhancers to increase the transdermal absorption rate of the active ingredients of the medicine. However, general chemical penetration enhancers, such as azone, surfactants, organic acids, etc., are likely to cause skin allergies, and long-term or high-dose use will cause damage to the skin. In recent years, penetration enhancers derived from natural plants have attracted more and more attention because of their mild action and less tox...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K47/46A61K31/137A61Q19/00A61P11/00
Inventor 庞玉新张新蕊于福来张影波王丹胡雄飞官玲亮
Owner 海南艾纳香生物科技发展股份有限公司
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