The invention relates to a drug with effects of bacterium resistance, disinfection, blood circulation promotion, blood stasis removal and immunity improvement. The drug with effects of bacterium resistance, disinfection, blood circulation promotion, blood stasis removal and immunity improvement comprises lucid ganoderma, ginseng, aerial parts of epimedium, radix astragali, polygonum cuspidatum, rhizoma gastrodiae, cordate houttuynia and licorice. The drug with effects of bacterium resistance, disinfection, blood circulation promotion, blood stasis removal and immunity improvement is prepared from the pour traditional Chinese medicines, and has the advantages of good treatment effects, small side-effect and short course of treatment. In addition, the drug with effects of bacterium resistance, disinfection, blood circulation promotion, blood stasis removal and immunity improvement can treat multiple diseases simultaneously, and has the effects of resisting bacteria, diminishing inflammation, relieving cough and asthma, reducing blood pressure and blood sugar, calming mood, soothing nerves, invigorating blood circulation, relieving pain, killing viruses, improving human immunity, treating tumors, prolong life and delaying aging.