The invention relates to a medicinal-edible traditional Chinese medicine composition for broad-spectrum cancer control and a preparation method thereof. The raw materials include 36 medicines such asroot of pilose asiabel, rhizoma alismatis from Fujian province, Xinjiang peony root, rhizoma polygonati, leaf of matrimony vine, herba patriniae, scabrous doellingeria rhizome and root, herba chelidonii, herba houttuyniae, herba taraxaci, indian kalimeris herb, buds of rhizoma polygoni cuspidati, dried orange peel, black nightshade herb, herba begoniae fimbristipulae, green folium perillae, herbasarcandrae, herb of waterplantain ottelia, herba scutellariae barbatae, raw liquorice root, rhizoma paridis chinensis, kiwi fruit, wild gecko, centipede, endothelium corneum gigeriae galli, goral horn, raw oyster shell, aspongopus, dung beetle, dryopteridis crassirhizomatis rhizoma, stem of sargentgloryvine, Zhejiang rhizoma atractylodis macrocephalae, toxin-extracted scorpio, root of beta vulgaris, herb of spica prunellae and root of sinkiang arnebia. The traditional Chinese medicine composition provided by the invention has the advantages of natural materials and scientific compatibility ofcomponents, is safe without toxic or side effects and can be effectively used for preventing and treating various kinds of cancers; the traditional Chinese medicine composition has the functions of consolidating essence and removing stasis, realizing target treatment, eliminating symptoms, ensuring recovery and the like; as a significant contribution of traditional Chinese medicine to the human society, the invention will finally throw a sprat and usher in the springtime of the world health service.