Multi-channel electrode sensor for detecting ovarian cancer markers

Abstract

The invention discloses a multi-channel electrode sensor for detecting ovarian cancer markers. The multi-channel electrode sensor comprises a substrate, an electrolytic tank region, four working electrodes, a reference electrode and an auxiliary electrode, wherein the electrolytic tank region is arranged on the substrate, and the working electrodes, the reference electrode and the auxiliary electrode are respectively arranged in the electrolytic tank region and are respectively connected with a multi-channel electrochemical working station detection circuit through mutually isolated electrode outgoing lines. The multi-channel electrode sensor for detecting the ovarian cancer markers has the advantages of convenience in manufacture, low cost, convenience in carrying, and easiness in minimization and integration, can simultaneously detect of four markers, is more convenient and rapid, is good in synchronization, is capable of reducing measurement errors, is remarkably increased in detection efficiency, and has important guiding significance for diagnosing, classifying and prognosing the tumor.

Description

technical field [0001] The invention relates to an electrode sensor, in particular to a multi-channel electrode sensor for simultaneously detecting four ovarian cancer markers, and belongs to the technical field of biological sensing and tumor detection. Background technique [0002] Ovarian cancer is one of the most common tumors in female reproductive organs, ranking third in incidence after cervical cancer and uterine body cancer. However, the number of deaths due to ovarian cancer ranks first in all types of gynecological tumors, posing a serious threat to women's lives. Due to the lack of specificity and sensitivity of the early symptoms of ovarian cancer, the early diagnosis rate is not high. The discovery and application of tumor markers is one of the commonly used methods for clinical detection of tumors, and is used for follow-up of tumors and observation of treatment effects. Simultaneous detection of mucin antigen CA12-5, alpha-fetoprotein AFP, human chorionic g...

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Problems solved by technology

[0003] At present, methods for determining ovarian cancer markers include radioimmunoassay, enzyme-linked immunoassay, and gold standard method. Although these methods have different advantages, they still have shortcomings. For example, radioimmunoassay has problems such as radioactive radiation and pollution. The immunoassay has the disadvantages of complex operation, high equipment requirements, and the need for specialized operators, while the gold standard method has the disadvantages of low specificity and sensitivity compared with the enzyme-linked immunoassay

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