Preparation method of potassium chloride sustained-release tablet
A technology for potassium chloride sustained-release tablets and a production method, which is applied in the field of production of potassium chloride sustained-release tablets, can solve problems such as differences in proportioning and production process differences, and achieves the effects of good ingredients and good quality
Active Publication Date: 2013-04-03
上海海虹实业(集团)巢湖今辰药业有限公司
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Problems solved by technology
[0002] At present, there are a large number of potassium chloride sustained-release tablets on the market. However, the medical effects of different brands of potassium chloride sustained-release tablets are very different. On the one hand, the proportions are different, and on the other hand, there are differences in the production process.
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[0036] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0037] The granulation ingredients of the potassium chloride sustained-release tablets (Potassium Chloride Sustained-release Tablets) of the present invention are: potassium chloride, hypromellose E (E5), lactose, hypromellose (E15) and microcrystalline Cellulose; the film coating composition of the potassium chloride sustained-release tablet is: acrylic resin (RS100), acrylic resin (RL100), fine talcum powder, triethyl citrate (TEC), 95% ethanol; the potassium chloride sustained-release tablet The sugar-coating ingredients of the release tablets are: sucrose, gelatin, talc and purified water.
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The invention discloses a preparation method of a potassium chloride sustained-release tablet, which comprises the following steps of crushing; weighing components; granulating: preparing an adhesive agent and wet particles; drying; granulating; totally mixing; tabletting; coating thin films: preparing components and coat materials; coating: preheating, spraying liquid, drying and curing; coating sugar-coating: preparing components and coating materials; preparing gelatin liquid; preparing mixed liquid; and coating, polishing, airing tablets, and inspecting tablets. The granulating components of the potassium chloride sustained-release tablet are potassium chloride, hydroxypropyl methylcellulose E (E5), lactose, hydroxypropyl methylcellulose (E15) and microcrystalline cellulose; the film components are acrylic resin (RS100), acrylic resin (RL100), fine talc powder, triethyl citrate (TEC) and 95 percent ethanol; and the sugar coating components are cane sugar, gelatin, talc powder and purified water. The manufacture method has the advantages that the potassium chloride sustained-release tablet with excellent quality can be produced.
Description
technical field [0001] The invention belongs to the field of medicine, in particular to a preparation method of potassium chloride sustained-release tablets. Background technique [0002] There are a large number of potassium chloride sustained-release tablets sold in the market, but the medical effects of different brands of potassium chloride sustained-release tablets are very different. On the one hand, the proportioning ratio is different, and on the other hand, there are differences in the production process. The invention provides a method for producing potassium chloride sustained-release tablets with better quality. Contents of the invention [0003] In view of this, it is necessary for the present invention to provide a method for producing potassium chloride sustained-release tablets with better quality. [0004] The present invention is achieved in that a kind of preparation method of Potassium chloride slow-release tablet, this preparation method comprises the...
Claims
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IPC IPC(8): A61K33/14A61K9/40A61K9/22A61P3/12
Inventor 金玉梁延波孔贵平黄斌
Owner 上海海虹实业(集团)巢湖今辰药业有限公司