Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer and preparation method thereof

A technology of methyl hydroxyethyl acrylate and dimethyl siloxane is applied in the field of highly processable siloxane derivative materials and their preparation, and can solve the problems of easy damage and inability to dissolve again.

Active Publication Date: 2013-04-03
SPRING FOUND OF NCTU
View PDF3 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In addition, silicone hydrogels and copolymerized polymer materials containing silicone hydrogels on the market must be cross-linked by ultraviolet light or thermal polymerization. After polymerization, they cannot be dissolved again. Sensitive or heat-sensitive drugs and active molecules

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer and preparation method thereof
  • Dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer and preparation method thereof
  • Dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] The present invention relates to a soluble amphiphilic copolymer, which is based on 2-hydroxymethyl acrylate (hereinafter referred to as HEMA), methacrylic acid (hereinafter referred to as MAA) and Terminal 3-propylamine polydimethylsiloxane (Poly(dimethylsiloxane), bis(3-aminopropyl)terminated, hereinafter referred to as PDMS) is synthesized in aqueous solution by chemical bonding. This soluble dimethylsiloxane-modified poly(2-hydroxyethyl acrylate-methacrylic acid) amphiphilic copolymer (pHEMA-MAA-PDMS amphiphilic copolymer, hereinafter referred to as pHEMA-MAA-PDMS amphiphilic copolymer) It can be completely soluble in alcohol solvents to facilitate subsequent processing requirements, and has adjustable hydrophilicity and hydrophobicity and good biocompatibility, so it can be used in applications such as anti-adhesion or drug release.

[0032] The pHEMA-MAA-PDMS amphoteric copolymer of the present invention includes amphoteric copolymers of the following structural f...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The present invention relates to a soluble dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer and a preparation method thereof. The soluble dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer is synthesized based on the following components according to a chemical bonding mode: 2-hydroxyethyl methacrylate (HEMA), methacrylic acid (MAA) and end3-propylamine polydimethylsiloxane (PDMS). The soluble dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer can be better dissolved in alcohol dissolvent for facilitating subsequent machining requirement, and furthermore has adjustable hydrophibility and hydrophobility and excellent bio-compatibility. Therefore the soluble dimethyl-siloxane-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer can be used for application in adhering prevention, medicine release, etc.

Description

technical field [0001] The invention relates to a highly processable siloxane derivative material and a preparation method thereof, in particular to a soluble dimethylsiloxane (PDMS) modified poly(2-hydroxyethyl acrylate-methyl Acrylic acid) (pHEMA-MAA) amphoteric copolymer and preparation method thereof. Background technique [0002] Due to the mechanical and physical properties of siloxane materials, it has become an emerging material trend in the industry in recent years. The world and the industry still need technological breakthroughs. [0003] Silicone hydrogel soft contact lenses, which are very common nowadays, have attracted widespread attention because of their comfortable wearing and greatly increased oxygen permeability. However, the hydrophobic nature of the surface of silicone hydrogel causes the deposition of proteins and lipids secreted by the eyes. , will cause eye discomfort and blurred vision, and have an adverse effect on prolonging the use time of cont...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C08F220/28C08F220/06C08F8/42A61K47/32
CPCC08F220/06C08F220/1808C08F222/10
Inventor 刘典谟黄筠淳许仲育
Owner SPRING FOUND OF NCTU
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com