Vaginal or rectal obturator and holding device thereof

Abstract

The invention relates to a vaginal or rectal obturator and a holding device thereof. The vaginal or rectal obturator and the holding device thereof comprise a vaginal or rectal obturator (8) and a vaginal or rectal holding device (9), wherein the vaginal or rectal obturator (8) comprises a plurality of claw arms (1) the ends of which are bonded together to become a to-be-held part; the front ends of the claw arms (1) are separated from each other; the front end of each claw arm (1) is provided with a spherical body (7); the holding device (9) is capable of sending the vaginal or rectal obturator (8) into the vaginal or the rectal; when the claw arms (1) prop open, the spherical body (7) is closely fit with the wall of the vaginal or the rectal, therefore continuous and long-term dosing is achieved, and the vaginal or the rectal obturator is not easy to slide out of the vaginal or the rectal due to the activities of animals. Furthermore, the vaginal or rectal obturator and the holding device thereof are simple to use and healthy.

Description

technical field [0001] The invention relates to a vaginal or rectal occluder and its holding device. Background technique [0002] At present, with the development of biological and pharmaceutical technology, animal experiments have become a basic experimental method in biology and medicine. Before drugs are clinically applied to humans, they usually need the help of some experimental animals, such as mice, rats, Rabbits, dogs, etc., to study the pharmacodynamics, pharmacology and toxicology of drugs. [0003] When treating some diseases such as vaginitis, administration routes such as oral administration, injection or external washing are not effective because they are not administered directly to the lesion. Treatment by vaginal administration has been widely used clinically, and many products are on the market, many of which require continuous administration to achieve an effective therapeutic effect. [0004] The invention patent application with the application number...

AI Technical Summary

Problems solved by technology

[0005] However, since experimental animals do not have good self-control unlike humans, and cannot reach the level of cooperation of humans, when these drug delivery devices in the prior art are used to administer drugs to the vagina or rectum of experimental animals, the experimental animals are usually more active. Especially for the discomfort caused by suppositories and gels at the vaginal or rectal administration sites, there will be rejection behavior, and the smooth muscles of the vagina or rectum will contract instinctively, which will cause the suppositories and gels to slip out of the vagina or rectum or deviate from the focus of administration site, unable to achieve the purpose of continuous and effective drug administration, and affect the experimental test results

Especially in the toxicity test, there will be certain requirements for the time of administration, such as about 30 minutes to 4 hours, the administration time is longer, and the use of the applicator in the prior art cannot achieve the purpose of the experiment

And if the animal is bound for a long time, it is not in line with animal ethics

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