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Traditional Chinese medicine composition for treating asthma, as well as preparation method and use of composition

A composition and drug technology, applied in the field of pharmaceutical compositions for the treatment of asthma, can solve problems such as tachycardia, tremor and QT interval prolongation, so as to inhibit eosinophil exudation, improve lung function, and relieve bronchospasm Effect

Inactive Publication Date: 2013-05-08
INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

beta 2 Although receptor agonists have a strong bronchodilator effect, they can cause tachycardia, palpitations, tremor and QT interval prolongation

Method used

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  • Traditional Chinese medicine composition for treating asthma, as well as preparation method and use of composition
  • Traditional Chinese medicine composition for treating asthma, as well as preparation method and use of composition
  • Traditional Chinese medicine composition for treating asthma, as well as preparation method and use of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Prescription: Angelica 2000g, Fritillaria 1500g, Sophora flavescens 1000g, licorice 500g.

[0024] Preparation:

[0025] 1) Weigh 2000g of Angelica sinensis and extract the volatile oil by steam distillation for later use, then concentrate and dry the residual Angelica sinensis water under reduced pressure to obtain extract;

[0026] 2) Mix Angelica dregs, Fritillaria 1500g, Sophora flavescens 1000g, and licorice 500g, and then reflux extraction with 60% ethanol for 3 times, each time for 1h, the ratio of solid to liquid is 1:10:8:8, and concentrated under reduced pressure to obtain paste, the extract is combined with the extract obtained in 1), freeze-dried to obtain freeze-dried powder;

[0027] 3) Uniformly mixing the extracted volatile oil with the lyophilized powder to prepare a medicinal powder.

Embodiment 2

[0029] Prescription: Angelica 10g, Fritillaria 1g, Sophora flavescens 10g, licorice 5g.

[0030] Preparation method: prepare the medicinal materials in the above weight ratio according to the method of Extraction Example 1, wherein the ethanol concentration is 70%.

Embodiment 3

[0032] Prescription: Angelica 15g, Fritillaria 9g, Sophora flavescens 10g, Licorice 1g.

[0033] Preparation method: the medicinal materials in the above weight ratio are prepared according to the method of Extraction Example 1, wherein the ethanol concentration is 65%.

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Abstract

The invention discloses a traditional Chinese medicine compound medicament composition for treating asthma and a preparation method of the composition. The medicament composition is of a medicament prepared from the raw materials of 1-20 parts of Chinese angelica, 1-20 parts of thunberg fritillary bulb, 1-10 parts of lightyellow sophora root and1-10 parts of liquorice root in weight part according to a ratio. The invention further provides the preparation method of the medicament composition, namely the traditional Chinese medicine compound medicament composition, as well as a use thereof in medicaments for treating the asthma.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound medicinal composition and a preparation method thereof, in particular to a medicinal composition for treating asthma, and belongs to the field of traditional Chinese medicine. Background technique [0002] Bronchial asthma (bronchial asthma, referred to as asthma) is a chronic airway inflammatory disease involving eosinophils, T lymphocytes, mast cells and other cells. This inflammation leads to increased airway reactivity and can cause narrowing of the airways, manifested by recurrent wheezing, dyspnea, chest tightness, or coughing. Asthma is one of the most common diseases in the world today, and it is also a world-recognized medical problem. It is listed as one of the four chronic diseases by the World Health Organization (WHO). [0003] In the past 20 years, with the global air pollution and environmental deterioration, the morbidity and mortality of asthma have been increasing year ...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P11/06
Inventor 邹忠梅陈虹高颖丁刚张宏武曹波
Owner INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI
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