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Traditional Chinese medicine composition having hypoglycemic effect

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition with hypoglycemic effect, to achieve the effect of overcoming cumbersome and ideal effect

Inactive Publication Date: 2014-05-21
CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to provide a novel Chinese medicine composition with hypoglycemic effect in view of the deficiencies of existing Chinese medicine compositions. Toxic and side effects, not only the effect of lowering blood sugar is very ideal, but also has a protective effect on the liver and kidney of the human body, and the quality is stable

Method used

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  • Traditional Chinese medicine composition having hypoglycemic effect
  • Traditional Chinese medicine composition having hypoglycemic effect
  • Traditional Chinese medicine composition having hypoglycemic effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The preparation of Chinese medicine composition of the present invention is as follows:

[0038] (1) Yizhiren powder preparation: take dry Yizhiren, crush to 200 mesh;

[0039] (2) Preparation of Trichosanthes Seed Oil: Dried Trichosanthes seeds were crushed, put into an extraction kettle for supercritical CO 2 extraction; extraction pressure is 35MPa, separation pressure is 6MPa-10MPa, extraction temperature is 45°C, separation temperature is 30°C, CO 2 The flow rate is 80L / h, and the extraction takes 2.5h;

[0040] (3) Take 100g of Yizhiren powder, add 25g of onion oil and 25g of Trichosanthes seed oil and mix directly to prepare the traditional Chinese medicine composition of the present invention.

Embodiment 2

[0042] On the basis of the traditional Chinese medicine composition prepared in Example 1, add starch 10g, mix and make the capsule of 0.5g / grain. Or add other commonly used auxiliary materials to prepare into tablets or pills.

Embodiment 3

[0044] The drug efficacy experiment data of the Chinese medicine composition prepared in embodiment 1 is as follows: (wherein said product refers to the pharmaceutical composition of the present invention prepared in embodiment 1)

[0045] 1. Experimental method

[0046] 1.1 Experimental grouping

[0047] Modeling: After the rats were fasted for 16 hours to measure the fasting blood glucose of the rats, streptozotocin was injected intraperitoneally at a dose of 35 mg / kg. After 7 days, the postprandial blood glucose of the rats was measured to be greater than 17.8 mmol / l, and the model was considered successful, and then the successful model rats were randomly divided into 7 groups according to the level of blood glucose level: type Ⅱ diabetes model group, 4 different doses of this product group (administrating 0.1, 0.2, 0.4 and 0.8 mg / kg of this product by intragastric administration each day), the vehicle control group (administered edible oil of the same quality), and the p...

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Abstract

The invention relates to the traditional Chinese medicine composition technical field, and concretely relates to a traditional Chinese medicine composition having hypoglycemic effect, the traditional Chinese medicine composition comprises the following components by weight: 90-110 parts of fructus alpiniae oxyphyllae powder, 15-35 parts of gualouzi oil, 15-35 parts of onion oil. According to the invention, complex compatibility of the traditional Chinese medicines and obvious toxic and side effect of lots of the traditional Chinese medicines can be overcome, the hypoglycemic effect is ideal, and the traditional Chinese medicine composition having the hypoglycemic effect has protection effect on liver and kidney of human body.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition with hypoglycemic effect. Background technique [0002] There are many traditional Chinese medicine compositions with hypoglycemic effect at present, such as: Patent Application No. 200610057532 discloses a compound hypoglycemic traditional Chinese medicine, which is mainly made of the following raw materials in proportions by weight: Schisandra 15-25 parts, asparagus 6-12 parts, 15-30 parts of Rehmannia glutinosa, 10-20 parts of Ophiopogon japonicus, 9-18 parts of ginseng. Ginseng is expensive. [0003] For example, patent application number 200510118948 discloses a hypoglycemic traditional Chinese medicine formula and its preparation method. The hypoglycemic traditional Chinese medicine formula (the specific dosage of 500 ml of oral liquid or 30 capsules or 30 tablets or 100 pills) is: Ginseng 50 gra...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/9062A61P3/10
Inventor 李赤翎
Owner CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY