Colloidal bismuth pectin capsule

A technology of colloidal bismuth pectin and capsules, which can be used in capsule delivery, medical preparations of non-active ingredients, digestive system, etc., and can solve the problems of affecting drug effects, slow decomposition speed, and sol formation

Active Publication Date: 2014-07-23
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Currently commercially available colloidal bismuth pectin capsules decompose slowly in gastric acid, and cannot quickly form sol in the stomach after oral administration, which affects the drug effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Add 300g of colloidal bismuth pectin (calculated as bismuth, converted to pure), 9g of micropowdered silica gel, and pregelatinized starch (990g) to a total weight of 3800g. Made in 1000 pieces.

[0019] Preparation:

[0020] Take 300g of colloidal pectin bismuth (calculated as bismuth, converted into pure), 9g of micropowder silica gel, and pregelatinized starch (990g), mix well, and wet granulate. Sieve, dry, and pack into capsule shells to make hard capsules, about 0.4g per capsule.

Embodiment 2

[0022] Add 200g of colloidal bismuth pectin (calculated as bismuth, converted to pure), 5g of micropowdered silica gel, and pregelatinized starch (1000g) to a total weight of 3800g. Made in 1000 pieces.

[0023] The preparation method is the same as above.

Embodiment 3

[0025] Add 400g of colloidal bismuth pectin (calculated as bismuth, converted to pure), 10g of micropowdered silica gel, and pregelatinized starch (1100g) to a total weight of 3800g. Made in 1000 pieces.

[0026] The preparation method is the same as above.

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PUM

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Abstract

The invention provides a colloidal bismuth pectin capsule. In the colloidal bismuth pectin capsule, aerosil and pregelatinized starch are mixed with colloidal bismth pectin in a specific proportion.

Description

technical field [0001] The invention relates to a colloidal bismuth pectin capsule. Background technique [0002] There are many kinds of medicines for treating gastric ulcer in the market, such as Livzon Dele, Sanjiu Weitai, etc., but the price is expensive, and the therapeutic effect is not satisfactory. These drugs can only relieve symptoms, and after a long time, the old disease will recur, and even cause other diseases. [0003] Colloidal bismuth pectin is a compound of variable composition formed by pectin and bismuth. Pectin-containing bismuth is calculated as bismuth (Bi), which should be 14.0% to 16.0%. Colloidal bismuth pectin is a new type of macromolecular bismuth agent with large molecular weight, stable colloid, and is difficult to be absorbed by the human body. It has no adverse reactions and side effects that are easily caused by similar drugs. Mainly used for the treatment of chronic gastritis. Colloidal bismuth pectin uses biological macromolecule pecti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K31/732A61K47/36A61K47/04A61P1/04
Inventor 王明刚任莉陈阳生
Owner CP PHARMA QINGDAO CO LTD
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