Catechin lozenge and its making method
A manufacturing method and technology of catechins, applied to medical preparations containing active ingredients, pharmaceutical formulas, pill delivery, etc., can solve the problems of changing molecular structure, deterioration, antibacterial and antiviral, etc., and achieve high biological activity, Guaranteed quality and curative effect, good quality and curative effect
Active Publication Date: 2013-07-10
云南易武正山茶叶有限公司
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Problems solved by technology
The existing buccal tablets usually do not contain catechins, because catechins are very easy to oxidize and lose their functional effects such as antiviral and antibacterial; even if they contain catechins, they are not high-ester catechins. Tea element can not solve the problem of antibacterial and antiviral
The existing buccal tablets usually do not wrap the Chinese herbal extract tightly, which makes the wrapped Chinese herbal extract easy to oxidize or even deteriorate, change its molecular structure, and lose its medicinal function; and most of them use more toxic organic solvents and metal ions
Method used
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Embodiment Construction
[0025] The present invention will be further described below in combination with principle diagrams and specific operation examples.
[0026] Such as figure 1 As shown, a kind of manufacturing method of catechin buccal tablet of the present invention mainly adopts microencapsulated ester plastid to wrap tea flavonoid crystal. To obtain high-ester type catechin-tea flavonoid crystals, green tea or oolong tea should be used as raw material, then soaked in 70%-90% alcohol for 1.5-3 hours, then filter out the tea dregs to obtain the infusion; then carry out salt leaching and desalinated water: wash the obtained soaking liquid into unsaturated salt solution for 1.5-3 hours, and filter off the sediment to obtain the filtrate; then adjust the pH value of the obtained filtrate to be acidic, preferably controlled between 1-6.5, and at 35 Carry out catalytic reaction at -85°C for 1.5-3 hours; then extract the reacted solution with 1:1 ethyl acetate to remove caffeine, you can choose 1...
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Abstract
The invention discloses a catechin lozenge and its making method. The making of the catechin lozenge through the method is in favor of obtaining a lozenge having high ester catechin-tea flavones, and guaranteeing the high biological activities of the high ester catechin-tea flavones, so the antibacterial antiviral capabilities are possessed. The catechin lozenge made through the method mainly comprises a microencapsulated lipidosome and the high ester catechin-tea flavones wrapped by the microencapsulated lipidosome. According to the invention, the making method of the catechin lozenge is in favor of obtaining the catechin lozenge having the high ester catechin-tea flavones, preventing catechins in the lozenge from oxidizing, storing the lozenge for a long term, and guaranteeing the quality and the curative effects of the lozenge; and catechin lozenge obtained through the method has the advantages of good quality and curative effects, antibiosis, antivirus, and high biological activities.
Description
technical field [0001] The invention relates to a medicine buccal tablet, in particular to a catechin buccal tablet containing catechin-tea flavonoid crystals. Background technique [0002] Existing studies have shown that: high-ester catechin has multidrug resistance, P-glycoprotein, drug resistance reversal, anti-squamous cell carcinoma, anti-oxidation, sterilization, anti-virus, anti-infection, anti-tumor, improving immunity and preventing oral infection. Strong special ability; it has the antitumor effect of cytotoxic sensitization on human multidrug-resistant oral cancer, protects the oral immune system, and protects the health of teeth; plaque etc. [0003] At the same time, most of the existing lozenges on the market are traditional sugar-coated macromolecular lozenges, which are mainly composed of polysaccharides or amylase as excipients and general Chinese herbal medicine extracts or polyphenolic compounds. The existing buccal tablets usually do not contain catec...
Claims
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Patent Timeline
Login to View More IPC IPC(8): A61K9/20A61K9/127A61K31/353A61K33/38A61K47/44A61P31/04A61P31/12A61P43/00A61P35/00A61P39/06A61P37/04A61P1/02
Inventor 不公告发明人
Owner 云南易武正山茶叶有限公司