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Traditional Chinese medicine composition having effect of reducing blood sugar and its use and preparation method

A composition and blood sugar-lowering technology, which is applied in the direction of drug combinations, medical preparations containing active ingredients, sugar-coated pills, etc., can solve the problems of complex production process, difficult synthesis, and large side effects, and achieve simple production process and wide range of drug sources , less toxic and side effects

Active Publication Date: 2013-07-24
金士力佳友(天津)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs can control and delay diabetes to a certain extent, the disadvantages of complex production process, high price, difficult synthesis, and large side effects are difficult to overcome.
Moreover, Western medicines are resistant, and patients must constantly change medicines

Method used

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  • Traditional Chinese medicine composition having effect of reducing blood sugar and its use and preparation method
  • Traditional Chinese medicine composition having effect of reducing blood sugar and its use and preparation method
  • Traditional Chinese medicine composition having effect of reducing blood sugar and its use and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The prescription of Chinese medicine composition is as shown in the table below:

[0027]

[0028]

[0029] Crumble jujube kernels and aloe vera, mix them with American ginseng, Kudingcha, hawthorn and Anemarrhena decoction pieces, add 8 times the amount of 70% ethanol and reflux to extract twice, each time for 1 hour, filter the extract, and concentrate the filtrate under reduced pressure (50°C -70°C) to a specific gravity of 1.0-1.25 (50°C); add 10 times the weight of the raw material to the filter residue and extract by microboiling and reflux twice, each time for 1 hour, filter the extract, and concentrate the filtrate under reduced pressure (50°C-70°C ) to a specific gravity of 1.04-1.06 (50°C), let it cool, add ethanol to make the alcohol content reach 50%, let stand for 24-48 hours, take the alcohol precipitation supernatant and filter, and concentrate the filtrate under reduced pressure (50°C-70°C) to a specific gravity of 1.0-1.25 (50°C); combine alcohol-...

Embodiment 2

[0032] The prescription of Chinese medicine composition is as shown in the table below:

[0033]

[0034] Crumble jujube seed and aloe vera, mix with American ginseng, Kudingcha, hawthorn and Anemarrhena decoction pieces, add 6 times the amount of 65% ethanol to reflux at 80°C for 3 times, each time for 0.5 hours, filter the extract, and reduce the filtrate at 40-50°C When concentrated under pressure to 50°C, the specific gravity is 1.1-1.2; add 8 times the weight of the raw material to the filter residue and extract with reflux at 90°C for 3 times, each time for 0.5 hours, filter the extract, and concentrate the filtrate under reduced pressure at 50°C-70°C to 50°C The specific gravity is 1.0-1.09, let it cool, add ethanol to make the alcohol content reach 40%, stand still for 12-24 hours, take the supernatant of alcohol precipitation and filter, the filtrate is concentrated under reduced pressure at 40-50°C to 50°C, and the specific gravity is 1.0-1.2; The alcohol-extracte...

Embodiment 3

[0037] Kudingcha 382.5g, hawthorn 382.5g, jujube seed 382.5g, Anemarrhena 510g, aloe 85g, American ginseng 127.5g, add water 1000ml, soak for 30 minutes, fry on medium heat for 1 hour, pour out the supernatant, add water 800ml, medium Cook on high heat for 40 minutes, pour out the supernatant. Combine the two supernatants and serve.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition having an effect of reducing blood sugar. The traditional Chinese medicine composition comprises, by weight, 3150 to 5850 parts of broadleaf holly leaf, 3150 to 5850 parts of haw, 3150 to 5850 parts of spina date seed, 4200 to 7800 parts of rhizoma anemarrhenae, 700 to 1300 parts of aloe, and 1050 to 1950 parts of American ginseng. The traditional Chinese medicine composition has effects of clearing heat and promoting fluid production, removing food retention and reducing phlegm, and tonifying qi and nourishing yin. The invention also provides a use of the traditional Chinese medicine composition and a preparation method of an extract. The invention discloses a specific extract of the traditional Chinese medicine composition, a specific dosage form, a use method and a use amount.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition with hypoglycemic effect, its application, its extract and a preparation method of some dosage forms. Background technique [0002] Diabetes mellitus is a chronic, metabolic disease characterized by chronic hyperglycemia and concurrent microvascular and macrovascular lesions caused by abnormal insulin secretion and action defects caused by multiple factors such as genetics, environment, and diet. At present, there is no effective drug or means to cure it, only to control blood sugar to a certain range so as to reduce and delay the occurrence of complications. At present, the drugs for hypoglycemia are mainly western medicines, including sulfonylureas (SUs), biguanides (BGs) and α-glucosidase inhibitors (α-GIs), thiazolidinediones ( TZD) and fast-acting insulin secretion-stimulating drugs. Although these drugs can control an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/28A61P3/10
Inventor 闫希军朱永宏李长文仝小林徐咏全崔瀚元凌芳
Owner 金士力佳友(天津)有限公司