Medicine composition resisting gout, promoting renal excretion, and repairing renal injury, as well as preparation method and application for same

A composition and anti-gout technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve myelosuppressive leukopenia, no uric acid urine excretion, eye damage; ⑤ Xanthine stones and other problems, to promote The effect of renal output

Active Publication Date: 2013-09-18
杨中林
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the treatment of gout, western medicines have different degrees of toxic and side effects and limitations. For example, allopurinols can only inhibit the activity of xanthine oxidase. The role of hyperuric acid in kidney injury, common side effects include: ① allergic rash, urticaria, drug fever, eosinophilia, etc.; ② myelosuppressive leukopenia, hemolytic anemia; High; ④ vasculitis and eye damage; ⑤ Xanthine stones; for example, benzbromarone can only promote the excretion of uric acid in urine, but it will aggravate the damage of uric acid to the kidneys. The main side effects are gastrointestinal dysfunction, renal colic Pain, gout acute attack, rash, etc., occasionally myelosuppression

Method used

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  • Medicine composition resisting gout, promoting renal excretion, and repairing renal injury, as well as preparation method and application for same
  • Medicine composition resisting gout, promoting renal excretion, and repairing renal injury, as well as preparation method and application for same
  • Medicine composition resisting gout, promoting renal excretion, and repairing renal injury, as well as preparation method and application for same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0127] Polygonum cuspidatum 1 weight part, turmeric 2 weight parts, salvia miltiorrhiza 3 weight parts, bamboo ginseng 1 weight part.

[0128] Preparation method: Weigh Polygonum cuspidatum, turmeric, Salvia miltiorrhiza and Panax ginseng, heat and reflux with 60% ethanol and extract three times, each extraction for 2, 2, and 1.5 hours, and the amount of ethanol used each time is 12, 10, and 8 hours of the medicinal materials respectively. Double the weight, filter, combine the 3 filtrates, recover ethanol under reduced pressure, and concentrate.

Embodiment 2

[0130] 2 parts by weight of knotweed, 3 parts by weight of turmeric, 1 part by weight of salvia miltiorrhiza, and 1 part by weight of bamboo ginseng. The preparation method is the same as in Example 1.

Embodiment 3

[0132] 3 parts by weight of knotweed, 1 part by weight of turmeric, 2 parts by weight of salvia miltiorrhiza, and 1 part by weight of bamboo ginseng. The preparation method is the same as in Example 1.

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Abstract

The invention discloses a medicine composition resisting gout, promoting renal excretion, and repairing renal injury, as well as a preparation method and an application for the same. The composition is prepared from the following components in parts by weight: 1-5 parts by weight of polygonum cuspidatum, 1-5 parts by weight of turmeric, 1-5 parts by weight of salviae miltiorrhizae, and 1-5 parts by weight of panax japonicus. The medicine composition can be prepared via an alcohol extraction method or a water extraction method. The medicine composition aforementioned has the remarkable effects of resisting gout, repairing renal injury, and increasing renal excretion amount.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and specifically relates to a pharmaceutical composition for resisting gout, promoting kidney excretion and repairing kidney damage, a preparation method and application thereof. Background technique [0002] Gout is a metabolic disease characterized by elevated levels of uric acid in the blood. With the improvement of people's living standards in our country, the incidence of hyperuricemia and gout is increasing year by year. Persistent gout can easily cause renal dysfunction, which can induce ischemic heart disease, kidney stones, obesity, hyperlipidemia, diabetes, important factors such as hypertension. In the treatment of gout, western medicines have different degrees of toxic and side effects and limitations. For example, allopurinols can only inhibit the activity of xanthine oxidase. The role of hyperuric acid in kidney injury, common side effects include: ① allergic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P19/06A61P13/12
Inventor 杨中林
Owner 杨中林
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